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The Effect of Lumbar CSF Drainage on the Neurologic Outcome Improvement in OHCA Underwent TTM

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1. Introduction: Global cerebral ischaemic-reperfusion brain injury following cardiac arrest (CA) can lead to intracranial hypertension and, occasionally, acute brain swelling. Even small increases in brain volume due to edema can result in harmful increases in intracranial pressure due to the

Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients

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Once the need for fibrinogen supplementation is confirmed, study participants will be randomized into one of two treatment groups (n=15 in each group): 1. Cryoprecipitate group (dose: 10 ml/kg; active control group) or 2. Fibrinogen Concentrate group (dose: 70 mg/kg; intervention group). There will

Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid

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Study design It is a single-center, prospective, double-blind, randomized, placebo-controlled trial. Study population All severely injured male and female patients with evidence of significant hemorrhage (systolic blood pressure <90 mmHg or heart rate >110 beats per minutes, or both) or had

QL Block With Exparel in Colectomy

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Participants in this study will receive exparel via an abdominal muscle nerve block procedure immediately prior to their operation. Participants will be in this study for 96 hours following surgery, which is typically 3 days. During participation, the study staff will review participant's electronic

Protecting Brains and Saving Futures

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Patient Experiences of IONM and Outcomes

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INTRODUCTION Intraoperative neuro-monitoring (IONM) is a 'SAT NAV' used by neurosurgeons to prevent injury to normal structures during brain and spinal surgery under anaesthesia. It involves the use of surface and implanted electrodes to observe spontaneous electrical activity of the brain or evoked

Versailles Hospital Cardiac Arrest Registry

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Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair

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This will be a double-blind, 3-arm, randomized controlled trial with a treatment 1: treatment 2: control allocation ratio of 1:1:1. Primary outcomes of interest are opioid requirements and pain scores over initial 72 hours of the postoperative period. Opioid requirements will be assessed by

12 Versus 20 mL PCB for D&E Cervical Prep

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Paracervical block (PCB) is a widely used, but largely unstandardized technique for pain management in gynecological procedures. From hysteroscopy to first trimester abortion procedures to dilator placement for dilation and evacuation, providers utilize the paracervical block to manage cervical

RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia

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Severe pneumonia is a serious infection in children which requires timely intervention. Management of severe pneumonia is done by appropriate antibiotics and supportive care. WHO recommendation is to use injection ampicillin four times a day for 3-5 days and injection gentamicin once a day for 3-5

Effects of Intraoperative Blood and Blood Product Consumption on Postoperative Results in Pediatric Cardiac Surgery

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Background: Blood products and intravenous fluids are frequently used in the treatment of children who have undergone cardiac surgery in order to maintain hemodynamic stability. Children undergoing cardiac surgery with cardiopulmonary bypass (CPB) are among the greatest pediatric users of allogeneic

RIAC - Registro Italiano Arresti Cardiaci (Italian Registry of Cardiac Arrest)

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The Italian Registry of Cardiac Arrest (RIAC) has been established in Italy by the Italian Resuscitation Council (IRC). It is a free web registry based on Utstein style data collection for all EMS and ICU departments that want to participate to this study. This research project will include all

Pain Management After Total Shoulder Arthroplasty

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This is a prospective, randomized, controlled study comparing post-operative pain scores, morphine sulfate equivalence consumption values, and adverse events in patients undergoing total shoulder arthroplasty with general anesthesia. Group1 will receive a pre-operative, ultrasound guided indwelling

Epileptic Potentials During Cardiac Surgery and Association With Postoperative Neurological Outcome

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The investigators will follow the STROBE guidelines to perform this prospective observational study. All patient demographics, co-morbidities and surgical details that are relevant to calculate the EuroSCORE will be recorded using our institutional automatic anesthesia record system. Laboratory

Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children

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Fluid therapy is aimed to compensate for fasting which is required for surgery, to meet the ongoing fluid losses and to maintain electrolyte balance during surgery. Fluid deficit of a healthy child who is not fed parenterally may be estimated by multiplying hourly maintenance requirement for fluid

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