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heart failure/повраћање
Веза се чува у привремену меморију
Страна 1 од 18 резултати
Benzisoxazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to benzisoxazole derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment
Indazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to Indazole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of
Oxyindole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to Oxyindole Derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of
Benzimidazolone compounds having 5-HT4 receptor agonistic activity
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TECHNICAL FIELD
This invention relates to novel benzimidazolone compounds. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, a method of treatment and use comprising the above compounds for the treatment of
Use of a benzo[b]thiopene-2-carboximidamide derivative
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The invention relates to the use of the benzo[b]-thiophene-2-carboximidamide derivative having formula I ##STR2## or pharmaceutically acceptable salts thereof, for the preparation of a medicament which is suitable for the treatment of heart failure, having high bioavailability without inducing
Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44)
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FIELD OF THE INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists
Benzimidazolone carboxylic acid derivatives
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
Benzimidazolone carboxylic acid derivatives
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
Benzimidazolone carboxylic acid derivatives
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone carboxylic acid derivatives. These compounds have selective 5-HT.sub.4 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof
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FIELD OF THE INVENTION
This invention relates to methods for discovering agonists and antagonists of the interaction between UDP-sugars (e.g.,UDP-glucose, UDP-galactose, UDP-glucuronic acid, and UDP-N-acetyl glucosamine) and their cellular receptor, human KIAA0001 receptor. The invention also
Triazolobenzodiazepines and their use as vasopressin antagonists
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This application is a national stage entry under 35 U.S.C. .sctn. 371 of PCT/IB05/002711, filed Aug. 12, 2005 which claims benefit of Provisional Application No. 60/616,601, filed Oct. 5, 2004.
This invention relates to novel compounds useful in therapy and to processes for the preparation thereof.
Triazole derivatives which inhibit vasopressin antagonistic activity
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This invention relates to novel compounds useful in therapy and to processes for the preparation of such compounds. It also relates to compositions containing such compounds, their use and intermediates used in their preparation.
WO 01/87855 discloses triazole derivatives as inhibitors of glycine
Nucleic acid encoding a bovine calcitonin receptor-like receptor (BECRLR)
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FIELD OF THE INVENTION
This invention relates to newly identified polypeptides and polynucleotides encoding such polypeptides, to their use in therapy and in identifying compounds that may be agonists or antagonists that are potentially useful in therapy, and to production of such polypeptides and
Human G-protein coupled receptor
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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
Antibodies immunospecific for a novel human G-protein coupled receptor family
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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
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