hyperhomocysteinemia/мучнина

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Hyperhomocysteinemia: could the post-methionine oral loading test sometimes be avoided?

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OBJECTIVE Measurement of homocysteinemia, a risk factor for venous and arterial thrombosis, is carried out in patients fasting for 12 hours and after an oral methionine load (PML). The procedure is time-consuming and several of the patients suffer from nausea and malaise. We wondered whether

[Hyperhomocysteinemia-related cerebral venous thrombosis].

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BACKGROUND Moderate hyperhomocysteinemia is a causal risk factor for atherosclerosis and venous thromboembolism. Recent researches have tried to find out a causal relationship. However, only a small number of cases have been reported on hyperhomocysteinemia and cerebral venous thrombosis in the

Acute myocardial infarction in a young patient with hyperhomocysteinaemia.

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Homocysteinuria is a rare inborn error of metabolism known to be associated with an increased risk of vascular events. A 36-year-old Caucasian man presented with a 2 day history of epigastric discomfort associated with nausea and sweating. He has a history of homocysteinuria and had been poorly

Spontaneous thrombosis of basilar artery aneurysm after subarachnoidal hemorrhage in a patient with thrombophilia and recurrent deep venous thrombosis.

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We report a patient with combined thrombophilia--protein C deficiency and mild hyperhomocysteinemia with total spontaneous thrombosis of a basilar tip aneurysm after subarachnoid hemorrhage, without neurological deficit. At admission, the patient had headache, drowsiness, and nausea, with no

Safety of the oral methionine load test: effects on the clinical performance and laboratory tests.

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BACKGROUND Hyperhomocysteinemia is a prothrombotic risk factor. Homocysteine is evaluated during fasting and after an oral methionine load (OML). OBJECTIVE To determine the safety of the OML test according to the general performance status and clinical laboratory tests. We studied healthy nonsmoking

Periconceptional folic acid containing multivitamin supplementation.

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OBJECTIVE A summary about the final results of the Hungarian double-blind placebo controlled randomised trial of periconceptional folic acid containing multivitamin and trace element supplementation. RESULTS The major finding is a significant prevention of the first occurrence of neural-tube defect,

Central retinal artery occlusion, an early sign of crizotinib resistance in an alk positive adenocarcinoma of lung: A rare case report.

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About 4% of non-small-cell lung carcinomas involve an EML4-ALK tyrosine kinase fusion gene and occur almost absolutely in carcinomas arising in non-smokers. Crizotinib, the first inhibitor of anaplastic lymphoma kinase (ALK), ROS1 and c-Met receptor kinase, has been used in the treatment of

Betaine: a potential agent for the treatment of hepatopathy associated with short bowel syndrome.

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BACKGROUND The hepatopathy associated with short bowel syndrome (SBS) is a multifactorial disease associated with poor prognosis. Besides intestinal transplantation, no other treatment has been shown effective. The current study evaluated the efficacy of betaine for the treatment of hepatopathy

Pharmacological treatment for Buerger's disease.

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Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities. The aetiology is unknown, but involves hereditary

Pharmacological treatment for Buerger's disease.

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BACKGROUND Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities. The etiology is unknown, but involves hereditary susceptibility,

Pharmacological treatment for Buerger's disease.

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Treatment of cobalamin C (cblC) deficiency during pregnancy.

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OBJECTIVE To report the successful pregnancy of a woman with methylmalonic acidemia and hyperhomocysteinemia, cblC type [cobalamin C (cblC) deficiency] (MIM 277400). METHODS Retrospective chart review. RESULTS A 24-year-old woman presented at 14 weeks gestation with nausea, self-restricted protein

Concurrent cerebral arterial and venous sinus thrombosis revealing celiac disease- a case report and literature review

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Background: Celiac disease is an autoimmune condition characterized by an inappropriate immune reaction against gluten. It classically presents as chronic diarrhea, bloating, and nausea in addition to malabsorption symptoms such as weight

Methionine-loading test: evaluation of adverse effects and safety in an epidemiological study.

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BACKGROUND Methionine loading test is commonly used to detect hyperhomocysteinemia in patients with arteriosclerosis and other conditions. As administration of methionine causes endothelial dysfunction in laboratory examinations, we explored whether loading with this compound leads to clinically

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