liver neoplasms/гојазност

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Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C

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HCC is the fourth leading cause of cancer mortality in 2018. The alarming incidence of HCC is explained by genetic and epigenetic alterations, as well as by the presence of risk factors: hepatitis C virus (HCV), hepatitis B virus (HBV) infection, alcohol consumption, smoking, diabetes, dietary

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

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The Mexican-American population accounts for 64.3% of the U.S. Hispanic population and is the fastest growing Hispanic subgroup. Non-alcoholic fatty liver disease (NAFLD) is a chronic disease associated with obesity that is highest in the nation for Mexican-American men. NAFLD consists of a spectrum

Testosterone in Bariatric Patients

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Introduction Obesity, poor physical fitness and low muscular strength are associated with all-cause mortality. Loss of bodyweight is commonly achieved by diet with or without exercise intervention. However, both diet and diet+exercise programs are often followed by weight regain and it is generally

Quantitative Ultrasound Techniques for Diagnosis of Nonalcoholic Steatohepatitis

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BACKGROUND - Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in Western countries. The more advanced form, nonalcoholic steatohepatitis (NASH) may evolve to fibrosis, cirrhosis, liver failure and liver cancer. Liver biopsy is the current reference standard for diagnosis

Global Osteopathic Treatment for Patients With NAFLD

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Randomized Quantitative Clinical Trial. There will be 48 participants randomly assigned codes numbers and placed into a treatment group or non treatment group with 24 candidates in each. The control group will not be receiving treatments whereas the experimental group will be receiving four global

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV

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There is a global epidemic of obesity and/or being overweight. Fatty liver disease associated with overweight/obesity, can cause liver inflammation, which can lead to scarring of the liver (cirrhosis), liver cancer and early death. It is predicted that fatty liver disease will become the number one

Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation

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Obesity:In adults, obesity is defined as a BMI of greater than 30 kg/m2. It is estimated that, by the year 2030, 38% of the world's adult population will be overweight and another 20% obese .An expert panel convened by the NIH stated that for the first time in history, the steadily improving

Mechanism of Sorafenib Resistance in Patients With Advanced Hepatocellular Carcinoma

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Introduction Hepatocellular carcinoma (HCC) is a major health problem, accounting for more than 626,000 new cases per year worldwide. It is the third highest cause of cancer-related death globally. In the west, the disease is diagnosed in 30 to 40% of all patients at early stages and is amenable to

LIVER FIBROSIS PREVALENCE IN FRANCE

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"This is the initial version of the FIBROFRANCE project which strated in 1997. Methods The strategy chosen is to screen advanced fibrosis in several groups of patients with different levels of risks in order to reconstruct the French prevalence thereafter. A national screening will be suggested

Treatment for Non-Alcoholic Fatty Liver With Different Doses of Vitamin E

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Non-alcoholic fatty liver disease (NAFLD) is the most common cause for liver test abnormalities in the western world, and an increasingly rising cause for liver-related morbidity and mortality. Vitamin E, a fat-soluble anti-oxidant was recently found to be an effective treatment for NAFLD; however,

Thermal Ablation in Larger Liver and Kidney Tumours

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Our group has developed a novel, interstitial induction coil device that has been designed to coagulate large tumours (≥3cm) through a single needle insertion using heat in the range 55-90 ◦C. [31]Our system consists of a helical coil that is loosely wound inside the tumour tissue or phantom and

Phase IIb Study to Evaluate the Efficacy and Safety of GFT505 Versus Placebo in Patients With Non-Alcoholic Steatohepatitis (NASH)

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The study duration per patient will be 80 weeks. A screening period (from 4 to 16 weeks) will precede a 52-week double-blind treatment period and a 3 months follow-up period. The study will be conducted in 270 patients (90 patients in the placebo arm, 90 patients in the GFT505 80mg arm, and 90

Trial of Hepaguard® in Adults With Nonalcoholic Steatohepatitis

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Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in affluent countries. Patients with nonalcoholic steatohepatitis (NASH), a severe form of NAFLD characterized by ballooning, lobular inflammation and liver fibrosis, have increased mortality rate and risk of

A Potential Novel Marker for Liver Fibrosis in NASH: the Soluble Secreted Form of the Human Asialoglycoprotein Receptor

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Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C

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The hepatitis C virus (HCV) chronically infects an estimated 240,000 in Canada and 170 million worldwide. Untreated, CHC is associated with significant long-term clinical consequences including cirrhosis, liver failure and hepatocellular cancer (HCC), and it is the most common indication for liver

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