5 резултати
FIELD OF THE INVENTION
This invention relates to nucleic acids, their encoded protease-activated receptor 3 proteins, and screening assays for agonists and antagonists of the protease activated receptor 3 proteins.
BACKGROUND OF THE INVENTION
Thrombin, a coagulation protease generated at sites of
FIELD OF THE INVENTION
This invention relates to nucleic acids, their encoded protease-activated receptor 3 proteins, and screening assays for agonists and antagonists of the protease activated receptor 3 proteins.
BACKGROUND OF THE INVENTION
Thrombin, a coagulation protease generated at sites of
FIELD OF THE INVENTION
The invention relates to pharmaceutical compositions for preventing destruction of pulmonary tissues before or during inflammation of the lungs, and to methods of forming and using such compositions.
BACKGROUND OF THE INVENTION
Endogenous degradation enzymes such as lipases
FIELD OF THE INVENTION
The present invention relates to a method and composition for treating mammals afflicted with a certain inflammatory disease. More particularly, the present invention relates to the treatment of certain pulmonary diseases and/or symptoms of the disease in mammals by
TECHNICAL FIELD
The present invention relates to a novel 4H-3,1-benzoxazin-4-one derivative and, more particularly, to 4H-3,1-benzoxazin-4-one derivatives having a serine protease inhibiting effect.
BACKGROUND ART
Proteases (proteolytic enzymes) present in a living body play a role in the