3 резултати
This application is a 371 of PCT/JP03/11420 filed on Sep. 8, 2003.
TECHNICAL FIELD
The present invention relates to a proline ester which is useful as a prodrug of enalaprilat, an agent useful in treatment of hypertension or cardiac failure, to drugs containing the ester, and to preparations
SUMMARY OF THE INVENTION
The compounds of the present invention are antagonists of the VLA-4 integrin ("very late antigen-4"; CD49d/CD29; or .alpha..sub.4.beta..sub.1), the .alpha..sub.4.beta..sub.7 integrin (LPAM-1 and .alpha..sub.4.beta..sub.p), and/or the .alpha..sub.9.beta..sub.1 integrin, and
This invention relates to novel peptides of the alpha conotoxin (.alpha.-conotoxin) class and their use in the treatment or prevention of pain, in recovery from nerve injury and in the treatment of painful neurological conditions such as stroke. The invention also relates to pharmaceutical