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Hesperidin and Diosmin for Treatment of COVID-19

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Research Background and Rationale At the end of December 2019, pneumonia of unknown origin was detected in the hospitals of Wuhan city, China, and reported to the WHO country office for the first time [1-3]. After a few days, the Chinese government has confirmed the human-to-human transmission of

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

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INCB7839 is an inhibitor of the ADAM (A Disintegrin and Metalloprotease) 10 and 17 proteases. Neuronal activity regulates glioma growth through neuroligin-3 (NLGN3). ADAM 10 is the protease responsible for NLGN3 release into the tumor microenvironment and represents a promising therapeutic

Usefulness of White Blood Cell Count (WBCC) During Infection in Geriatric Patient

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Study design Observational prospective study The subjects Number of subjects 200 subjects: Average value CRP: group 1: 55; group 2: 84 Average standard deviation: 70.52 Power 80%: 158 deelnemers Power 90%: 202 deelnemers alpha = 0.05 2-sample T-test. Inclusion criteria Acute inflammation is defined

Dyspnea in Chronic Thromboembolic Pulmonary Hypertension

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Rationale: In patients with pulmonary embolism, most assessments of the burden of blood clots and possible related complications, currently rely on chest imaging and heart ultrasound. While these tests are useful in charting the course of the disease, they offer little about how the function of the

Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Elective Caesarean Section

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RESEARCH QUESTION Does intravenous Tranexamic Acid (TXA) 10mg/kg plus Oxytocin 5 International Units (IU) result in a lower incidence of primary postpartum haemorrhage compared to Oxytocin alone after elective caesarean section. RATIONALE FOR THE RESEARCH Postpartum haemorrhage (PPH) is a major

Preoperative Glucocorticoid Use in Major Hepatectomy

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Introduction: Major hepatectomy lead to significant postoperative anatomical and physiological changes. The liver dictates the systemic metabolic environment and helps maintain homeostasis. When segments of liver are removed, it is challenged to regenerate and restore cellular volume, as well as

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

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OBJECTIVES: Primary - To evaluate the difference in overall survival of patients with clinically localized prostate cancer with unfavorable prognostic features between a) standard treatment (androgen-deprivation therapy [ADT] + radiotherapy) and b) standard treatment with the addition of 24 months

Effect of Yoga on Objective and Subjective Menopausal Hot Flashes

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Hot flashes and/or night sweats are the most common and troubling symptoms associated with menopause. It is estimated that 64% to 87% of women report experiencing hot flashes for an average of about 4 years. For many women, these symptoms are frequent and severe enough to become debilitating and

The Feasibility of Physical Activity in Advanced Cancer Patients

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Background Information Cancer is one of the leading causes of mortality and morbidity worldwide[1]. The resultant morbidities of cancer and its treatment are manifold; common physiologic symptoms include pain, muscle weakness and fatigue, whereas common psychological symptoms include depression,

Effect of Darbepoetin Alfa (Aranesp®) on Anemia in Patients With Advanced Hormone Independent Prostate Cancer

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In the past, prostate cancer has been regarded a relatively benign disease, which elderly men were expected to die with rather than from, however, prostate cancer has become the second most common non-skin cancer in Danish men and the second most common cause of male cancer death. Two out of three

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