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Anti-seizure activity of the aqueous leaf extract of Solanum nigrum linn (solanaceae) in experimental animals.

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BACKGROUND Solanum nigrum is claimed in traditional medical practice, to be useful in the treatment of epilepsy in some parts of Nigeria. OBJECTIVE To study the anti-convulsant property of the aqueous extract of the leaves of S. nigrum in chicks, mice and rats. METHODS Aqueous extracts were

Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents.

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BACKGROUND Solanum sisymbriifolium Lam. (Solanaceae), commonly known as sticky nightshade, is traditionally used for central nervous system (CNS) disorders. Although solasodine has been isolated from this plant, little is known about its anticonvulsant and CNS depressant actions. OBJECTIVE We

Antidepressant, anxiolytic and adaptogenic activity of torvanol A: an isoflavonoid from seeds of Solanum torvum.

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The objective of this study was to determine the effect of torvanol A (10 and 30 mg/kg) isolated from Solanum torvum as antidepressant, anxiolytic and adaptogenic. Forced swim test (FST), tail suspension test (TST), elevated plus maze (EPM) test, light dark apparatus (LDA),

Zebrafish bioassay-guided microfractionation identifies anticonvulsant steroid glycosides from the Philippine medicinal plant Solanum torvum.

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Medicinal plants used for the treatment of epilepsy are potentially a valuable source of novel antiepileptic small molecules. To identify anticonvulsant secondary metabolites, we performed an in vivo, zebrafish-based screen of medicinal plants used in Southeast Asia for the treatment of seizures.

Intoxication by Solanum fastigiatum var. fastigiatum as a cause of cerebellar degeneration in cattle.

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A bovine cerebellar disorder of recurrent seizures characterized by loss of equilibrium, extension of the head and thoracic limbs, opisthotonus, nystagmus and falling to the side or backwards is described from 16 farms in the Brazilian state of Rio Grande do Sul. The main pathologic features were

Awareness and current knowledge of epilepsy.

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Epilepsy is a severe neural disorder that affects approximately fifty million individuals globally. Despite the fact that for most of the people with epilepsy, convulsions are better controlled by current accessible antiepileptic medicines, yet there are more than 30% of individuals affected with

Potato (Solanum tuberosum) juice exerts an anticonvulsant effect in mice through binding to GABA receptors.

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Naturally occurring benzodiazepines have been identified in regular food such as wheat and potato, but there is still no evidence that potato extracts can affect CNS responses in vivo. Here we found that undiluted potato juice and potato juice diluted with saline 1 : 2 administered 10 min

Convulsive action of (25S)-isosolafloridine isolated from Solanum pseudo-quina bark.

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The crude ethanolic extract prepared from the stem bark of Solanum pseudo-quina produced excitatory effects dominated by convulsions in rats and mice. Solvent extraction followed by alumina column chromatography resulted in the isolation of a pharmacologically active material (AP) which was

Maldronksiekte in cattle: a neuronopathy caused by Solanum kwebense N.E. Br.

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A neurological disease of cattle (maldronksiekte), occurring in a localized area of the Northern Transvaal, was experimentally reproduced by feeding Solanum kwebense plants to cattle. The disease is characterized by temporary loss of balance and transient epileptiform seizures precipitated by a

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Herbal & Natural Medicine

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