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Effects of Training and Detraining on Postmenopausal Breast Cancer Survivors

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The present study aimed to verify the effects of 12 weeks of resistance exercise training and successive 12 weeks of detraining on body composition (Body Mass, Body Mass Index, Fat Mass, and Fat-Free Mass), lipid profile (Triglycerides, Total Cholesterol, LDL-Cholesterol, HDL-Cholesterol), muscle

Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight Women

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PRIMARY OBJECTIVE: I. Evaluate the feasibility of a diet and exercise intervention to decrease body fat in postmenopausal women with normal body mass index (BMI) but high body fat (trunk fat mass 9.4 kg, the 50th percentile of normal BMI women in the Women's Health Initiative [WHI]). SECONDARY

Plant Sterol INtervention for Cancer Prevention (PINC)

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Delivery of cholesterol to extra-hepatic tissues by LDL has a profound impact on different host cell types, many of which themselves have been implicated in BCa metastasis and chemoresistance. Despite accumulating data, it is still unknown how host-cells help breast tumours metastasise or evade

Docosahexaenoic Acid (DHA) for Women With Breast Cancer in the Neoadjuvant Setting

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Red Clover and Lifestyle Changes to Contrast Menopausal Symptoms in Premenopausal Breast Cancer Patients Given Tamoxifen

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Premenopausal women with ER-positive breast cancer treated by surgery and receiving postoperative tamoxifen with or without LHRH analogues, who may have received pre or postoperative chemotherapy, or immunotherapy (for HER2-positive disease), are recruited to a double-blind randomized clinical

Ketogenic Diet: a Novel Metabolic Strategy to Treat Lymphedema Patients?

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Lymphedema is a debilitating disorder that severely impairs the quality of life of the patients and requires life-long attention. It can be classified as primary or secondary, based on the etiology. Primary lymphedema is a rare, congenital disorder caused by inherited genetic mutation on a number of

Aerobic Training in Treatment for Breast Cancer

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Introduction. Breast cancer is one of the leading causes of morbidity and mortality in the world.Treatment with hormone therapy reduced the likelihood of tumor recurrence and metastasis in the patient. However, it has adverse effects such as: loss of bone mineral density, increase in body weight,

Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer

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PRIMARY OBJECTIVES: I. To determine the recommended phase II dose of topical bexarotene 1% (weight by weight [w/w]) gel for evaluation in healthy women. (Dose Escalation Group) II. Conduct an intervention of topical 1% bexarotene gel to an unaffected breast of healthy women at high risk for breast

Tetranectin as a Novel Obesity-associated Adipokine for Regulating Lipid Accumulation

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Adipose tissues were obtained from the breast of breast cancer patients with 0 to 1 progression stage. All participants gave permission and the study was approved by the Ethics Committee of National Taiwan University Hospital as no. 9461701203. From 2012 to 2013 in National Taiwan University

STI.VI. Study: How to Improve Lifestyles in Screening Contexts

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The study aims to evaluate the effectiveness of intervention models on diet and physical activity. The study randomizes eligible subjects into four groups: Diet group, Physical Activity group, Physical Activity and Diet group and "Usual Care" control group. To each group a specific intervention is

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

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PRIMARY OBJECTIVES: I. To determine if treatment with a combination of metformin and doxycycline can increase the percentage of cells that express Caveolin-1 in the cancer associated fibroblasts of patients with breast, or uterine, and cervical cancers. SECONDARY OBJECTIVES: I. To determine the

Effects of Adjuvant Endocrine Therapy With Aromatase Inhibitors on the Postoperative Lipid Levels in Postmenopausal Breast Cancer Patients

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The study subjects are composed of postmenopausal women with hormone receptor-positive breast cancer who have received exemestane, anastrozole or letrozole followed by testing of safety variables such as low-density lipoprotein- cholesterol (LDL-C), triglyceride(TC), total cholesterol, high-density

Anticancer Treatment of Breast Cancer Related to Cardiotoxicity and Dysfunctional Endothelium

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1. Background During the past 30 years, survival of breast cancer patients has improved substantially due to earlier diagnosis, improved surgical techniques, introduction of new combination of chemotherapy, new hormonal treatment, introduction of targeted treatment, and refinement of radiation

Life ImproVed by Exercise (LIVE Trial)

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In this prospective randomized controlled trial patients with previous breast cancer will be randomized into two treatment arms: 1. Control Group of Usual Physical Activity 2. Intervention Group of Increased Physical Activity No specific intervention will be performed In the patients randomized in

Evaluation of a Physical Activity Program in Overweight Breast Cancer Patients

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Rationale: Patients diagnosed with breast cancer generally have a fairly well prognosis with estimated average survival rates of 73% and five year survival rates of 89% in developed countries (1). However, women who are obese at the time of breast cancer diagnosis seem to be at risk for a worse

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