The Effects of Rhus Coriaria L. on Body Weight
Nyckelord
Abstrakt
Beskrivning
Rhus coriaria L.(Rhus) is a well-known spice widely consumed in the world which has also been utilized extensively for medicinal purposes. The antioxidant components of this plant made it a favorable target for laboratory and animal studies in different conditions such as oxidative stress cytotoxicity, diabetes and hyperlipidemia. Rhus (Somagh) is found in temperate and tropical regions worldwide, often growing in areas of marginal agricultural capacity. Rhus is used as an herbal remedy in traditional medicine because of its assumed analgesic, antidiarrheic, antiseptic, anorexic and antihyperglycemic properties. The fruits of Rhus contain flavonols, phenolic acids, hydrolysable tannins, anthocyans and organic acids such as malice, citric and tartaric acids. Some studies have shown that polyphenols could have beneficial effects on cardiovascular disease and cancer and could be regarded as bioactive compounds with a high potential health-promoting capacity. Phenolic compounds inhibit lipid peroxidation, scavenge the superoxide anion and hydroxyl radical, and enhance the activities of detoxifying enzymes.
The aim of this study is to evaluate the effects of Rhus coriaria L. (Rhus) commonly known as Somagh on body weight.
Datum
| Senast verifierad: | 08/31/2016 |
| Först skickat: | 04/25/2016 |
| Beräknad anmälan inlämnad: | 04/25/2016 |
| Först publicerad: | 04/27/2016 |
| Senaste uppdatering skickad: | 08/21/2018 |
| Senaste uppdatering publicerad: | 08/22/2018 |
| Faktiskt startdatum för studien: | 04/30/2016 |
| Uppskattat primärt slutdatum: | 08/31/2016 |
| Beräknat slutfört datum: | 08/31/2016 |
Tillstånd eller sjukdom
Intervention / behandling
Drug: Rhus
Drug: Placebo
Fas
Armgrupper
| Ärm | Intervention / behandling |
|---|---|
| Experimental: Rhus 500 mg twice daily after meal for 6 weeks | Drug: Rhus 500 mg twice daily after meals for 6 weeks |
| Placebo Comparator: Placebo 500 mg twice daily after meal for 6 weeks | Drug: Placebo 500 mg twice daily after meals for 6 weeks |
Urvalskriterier
| Åldrar berättigade till studier | 18 Years Till 18 Years |
| Kön som är berättigade till studier | All |
| Accepterar friska volontärer | Ja |
| Kriterier | Inclusion Criteria: - Body mass index (BMI) >= 25 kg/m2 Exclusion Criteria: - Diabetes mellitus - Hypo. or hyperthyroidism - Any systemic illnesses e.g. liver cirrhosis, acute or chronic renal failure, heart failure - Use of drugs: Weight lowering agents, glucocorticoids, Oral contraceptive pills. - Pregnancy - History of allergic reaction to Somagh |
Resultat
Primära resultatåtgärder
1. Body Mass Index [6 weeks]
Sekundära resultatåtgärder
1. Waist Circumference (cm) [6 weeks]
2. Hip Circumference (cm) [6 weeks]
3. Leptin (ng/ml) [6 weeks]
4. Insulin (mU/l) [6 weeks]
5. Fasting Blood Glucose (mg/dl) [6 weeks]
6. Number of patients with adverse event [6 weeks]
