Essential Oils With and Without Alcohol: Substantivity and Antiplaque Effect
Nyckelord
Abstrakt
Datum
Senast verifierad: | 04/30/2017 |
Först skickat: | 04/29/2017 |
Beräknad anmälan inlämnad: | 05/07/2017 |
Först publicerad: | 05/08/2017 |
Senaste uppdatering skickad: | 05/07/2017 |
Senaste uppdatering publicerad: | 05/08/2017 |
Faktiskt startdatum för studien: | 05/01/2017 |
Uppskattat primärt slutdatum: | 07/30/2017 |
Beräknat slutfört datum: | 08/30/2017 |
Tillstånd eller sjukdom
Intervention / behandling
Drug: Essential oils (Listerine Mentol)
Drug: Alcohol free essential oils
Other: Water
Fas
Armgrupper
Ärm | Intervention / behandling |
---|---|
Active Comparator: Essential oils (Listerine Mentol) a single mouthwash with 20 ml of essential oils for 30 seconds
20 ml rinses for 30 seconds with essential oils/2 times daily (1/0/1). | Drug: Essential oils (Listerine Mentol) all subjects will perform all interventions of all arms |
Placebo Comparator: Water a single mouthwash with 20 ml of sterile water for 30 seconds
20 ml rinses for 30 seconds with sterile water/2 times daily (1/0/1). | Other: Water all subjects will perform all interventions of all arms |
Experimental: Alcohol free essential oils a single mouthwash with 20 ml of alcohol free essential oils for 30 seconds
20 ml rinses for 30 seconds with alcohol free essential oils/2 times daily (1/0/1). | Drug: Alcohol free essential oils all subjects will perform all interventions of all arms |
Urvalskriterier
Åldrar berättigade till studier | 20 Years Till 20 Years |
Kön som är berättigade till studier | All |
Accepterar friska volontärer | Ja |
Kriterier | Inclusion Criteria: - Systemically healthy adults. - Minimum of 24 permanent teeth. - No gingivitis (Community Periodontal Index score = 0). - No periodontitis (Community Periodontal Index score = 0). - Absence of untreated caries. Exclusion Criteria: - Smoker or former smoker. - Presence of dental prostheses. - Presence of orthodontic devices. - Antibiotic treatment or routine use of oral antiseptics in the previous 3 months. - Presence of any systemic disease that could alter the production or composition of saliva. |
Resultat
Primära resultatåtgärder
1. Change in the Bacterial viability (%) (substantivity) [Baseline, 30 seconds, 1 hour, 3 hours, 5 hours and 7 hours after the single application]
2. Bacterial viability (%) (antiplaque effect) [10 hours after the last mouthwash]
3. Change in the Biofilm Thickness (Microns) (substantivity) [baseline, 30 seconds, 1 hour, 3 hours, 5 hours and 7 hours after the single application]
4. Biofilm Thickness (Microns) (Antiplaque effect) [10 hours after the last mouthwash]
5. Covering Grade (%) (antiplaque effect) [10 hours after the last mouthwash]