Pachyonychia congenita (often abbreviated as 'PC') is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different keratin genes. Pachyonychia congenita is often associated with thickened toenails, plantar keratoderma, and plantar pain.
Pachyonychia congenita is characterized by a clinical triad present in 97% of people with PC by the time they turn 10 years old:
Plantar pain that may require some patients to use wheelchairs, canes, crutches, and pain medications ...
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* All information baseras på publicerad vetenskaplig forskning