Assessment of the Effect of Extract Formulation of Date Palm Kernel on Facial Skin Wrinkles: Biophysical Measurements and Digital Profilometry.

Previous studies have shown that the date palm kernel contains plenty of phytochemicals of potential rejuvenation benefits to skin. The aim of this study was to investigate a cream form containing date palm kernel extract (DPKE) on facial wrinkle reduction and objective skin parameters in healthy subjects. A cream form containing 5% DPKE was prepared and applied twice daily for 8 weeks on the facial skin of 43 volunteers. Biophysical measurements including skin hydration, elasticity, and pigmentation as well as optical scanning of skin surface were carried out after 4 and 8 weeks. Significant improvement in facial skin hydration, elasticity, and melanin concentration together with reduction in the wrinkle size and depth were observed at the two time points of measurements. In addition, DPKE cream was extremely well tolerated by the facial skin of study participants. The work herein demonstrates and validates the use of cream form containing 5% DPKE over placebo against fine lines and wrinkles, skin pigmentations, skin hydration, and elasticity. This effect may be attributed to synergism of major phytochemicals and phytosterols present in DPKE.