Cerebral arteriovenous malformation presenting with polycythemia vera: A case report and literature review.
Nyckelord
Abstrakt
BACKGROUND
Cerebral arteriovenous malformations (AVM) usually present with headache, hemorrhage, or seizure. Erythropoietin (EPO) has demonstrated protective effects against ischemia within the CNS.
METHODS
The authors report a patient with a cerebral AVM and concurrent polycythemia associated with elevated serum EPO. Systemic EPO levels declined acutely after resection of the patient's AVM, and the polycythemia resolved in the following months.
CONCLUSIONS
Polycythemia secondary to a cerebral AVM, in the absence of extra-cerebral vascular lesions, has not been described in the literature.
CONCLUSIONS
The authors explore the mechanisms by which this patient's cerebral AVM could have induced EPO production within the brain, manifesting as polycythemia.
