Voprosy meditsinskoi khimii
[Fucosylation of serum proteins in stomach cancer].
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Content of fucose and of fucosylated protein fractions was studied in blood serum of healthy donors as well as in blood serum of patients with chronic gastritis and with stomach cancer. Concentration of fucose was increased in blood serum under conditions of the tumor generalization. At the same time, content of fucosylated albumin was elevated within early steps of stomach cancer, while the content of fucosylated globulins was decreased. Estimation of albumin-bound fucose might be used in diagnosis of stomach cancer.
