Japanese journal of cancer research : Gann 1988-Jan
Gallium citrate, a new sensitizer of cells to hyperthermia.
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The killing effects of heat were studied on cultured mammalian cells (L5178Y) pre-incubated with gallium (Ga) citrate, which is a popular tumor-imaging diagnostic agent. The cells showed higher sensitivity to heat when they were pre-incubated with Ga-citrate. The pre-incubated cells showed decreased ATP levels, and this may be responsible for the heat-sensitizing effect.
