[One Case of Multiple Myeloma with Central Never System Infiltration].

OBJECTIVE

To analyses and summarize a case of multiple myeloma with disseminated infiltration in central nervous system.

METHODS

The results of laboratorial examination and clinical data were analyzed and compared in the light of published literatures.

RESULTS

The headache and diplopia were caused by infiltration of multiple myeloma cells to the central nervous system. Unlike those reported in the literatures, this case was a rare case of disseminated infiltration inside the brain, and plasma cells were CD56+, this patient has not yet accepted any multiple myeloma-associated treatment as like that reported in the literatures. And different from cases reported, this patient showed a good response to the intrathecal chemotherapy.

CONCLUSIONS

Whether this good response is due to a heterogeneity of MM or effect of treatment-associated drug is still to be decided.