[Study on Chemical Constituents of Kalimeris indica].

OBJECTIVE

To study the chemical constituents from the active fractions of Kalimeris indica.

METHODS

The chemical constituents were extracted of different concentrations and isolated by silica gel, Sephadex LH-20 column and preparative HPLC. The chemical structures were further elucidated by the physicochemical characters, MS and NMR spectral data.

RESULTS

Fourteen compounds were isolated and identified as α-spinasterol(1), dibutylphthalate (2), (22E,24R)-5α,8α-epidioxy-ergosta-6,22-dien-3β-ol(3), oleanolic acid(4), coniferyl alcohol(5), umbelliferone(6), syringaresinol(7), 15-oxo-14,16H-strictic acid(8), lariciresinol(9), (Z)-3,7,11-trimethyl-1,6-dodecadien-3,10,11-triol(10), neoechinulin A(11), pinoresinol(12), 4-allyl-3,5-dimethoxyphenol(13), and 3,4,5-tri-methoxyacetophenone (14).

CONCLUSIONS

Except compound 1, the other compounds are isolated from this genus for the first time.