Persistent Tunica Vasculosa Lentis as an Independent Risk Factor for Treatment in Retinopathy of Prematurity

This was a 1:1 nested case-matched, consecutive, single physician, retrospective series assessing the risk of treatment for ROP in patients with persistence tunica vasculosa lentis (TVL) on neonatal screening examination. The rate of meeting the criteria for treatment and having zone 1 disease were increased in the TVL group (30.85% vs 10.64%, p<0.001, odds ratio of 4.80) and (15.96% vs 2.12% p= 0.002, odds ratio of 7.50) respectively. Persistence of TVL is a poor prognostic sign in ROP with higher rates of treatment requirement and zone 1 disease when compared to age and birthweight matched controls.

Keywords: Anti-VEGF; Laser; Retinopathy of prematurity; Treatment; Tunica vasculosa lentis.