4 hydroxyanisole/karies

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Differential distribution and placental transport of 2- and 3-t-[methyl-14C]butyl-4-hydroxyanisole (BHA) in pregnant mice.

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The placental transport and localization in fetal and maternal tissues of 14C-BHA isomers, 2-t-[methyl-14C]butyl-4-hydroxyanisole (2-BHA) and 3-t-[methyl-14C]butyl-4-hydroxyanisole (3-BHA), were studied in pregnant mice by whole-body autoradiography techniques. BHA isomers were given (iv 50

Butylated hydroxyanisole affects immunomodulation and promotes macrophage phagocytosis in normal BALB/c mice.

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Butylated hydroxyanisole (BHA), a synthetic antioxidant, has been used in fat and fatty foods to prevent oxidative deterioration. However, the functions of BHA on immune responses in normal mice remain elusive. The aim of the present study was to investigate the effects of oral treatment of BHA on

Experimental chemotherapy of murine melanomas: is there a discrepancy compared to clinical experience?

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There has been a discrepancy between promising results of experimental chemotherapy in animal melanoma models and clinical response rates. This inconsistency seems to reflect weak points of the assays used so far to monitor the response of melanoma cells to chemotherapeutic agents. Therefore a less

Factors effecting the induction of rat forestomach hyperplasia induced by Swedish oral smokeless tobacco (snus).

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Long term exposure to oral smokeless tobacco may induce lesions in the oral cavity characterized by a hyperplastic epithelium. The possible role of nicotine and the physical properties of oral tobacco for developing these lesions, as well as of dysplasia and neoplasia is unclear. Low nitrosamine

Studies in vivo by electron spin resonance of free radical mechanisms implicated in UV-induced skin photocarcinogenesis.

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Synopsis Solar ultraviolet radiation (UVR) is implicated in many types of skin damage, such as photodermatoses, photoageing, erythema, pigmentation, skin cancer etc. Free radicals and reactive oxygen species are considered to play an important role in cutaneous photocarcinogenesis. But skin is

Inhibition by blueberries (bilberries) and extract from milk thistle of rat forestomach hyperplasia induced by oral smokeless tobacco (Swedish snus).

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The aim of this study was to identify palatable additives which have a significant protective action against soft tissue changes in the oral cavity caused by Swedish smokeless tobacco ("snus"), and that satisfy existing legal requirements. Although the cancer risk from snus is extremely low, long

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