ageusia/inflammation

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Recurrent hypogeusia in a patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).

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Hypogeusia, a condition with diminished sense of taste, is caused by several conditions, including zinc deficiency and as a side-effect of drugs, but is not common in neurological disorders. A 55-year-old Japanese man with a 30-year history of chronic inflammatory demyelinating

[The specific features of the pathological morphology and pathogenesis of scleroma: morphological, histochemical, and electron microscopic studies].

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The specific features of the pathological histology of scleroma have been continuously studied at the Pathology Department of the Lvov Medical University since 1945. A total of 1025 biopsy specimens from 656 patients with scleroma were examined. Along with diverse dystrophic and metaplastic changes

[Dysgeusias].

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This is a review of multiple pathologic conditions associated with altered taste perception and identification. We stated the steps and the molecular basis of this sense. This paper includes two cases that exemplify two distinct types of dysgeusia; case, 1 a 48 year old man who had clinical

Correlation between viral load, plasma levels of CD4 - CD8 T lymphocytes and AIDS-related oral diseases: a multicentre study on 30 HIV+ children in the HAART era.

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This experimental retrospective multicenter study carried out on 30 seropositive children treated with Highly Active Antiretroviral Therapy (HAART), between the ages of 18 months and 14 years, in the clinical categories Centers for Disease Control (CDC) classification 1993 A (mildly symptomatic), B

Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety.

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BACKGROUND Vismodegib is a novel hedgehog pathway inhibitor approved to treat advanced and metastatic basal cell carcinoma (BCC) in the United States. Several studies have demonstrated efficacy for treatment of new and existing BCC in both basal cell nevus syndrome (BCNS) and non-BCNS patients.

Taste evaluation in adolescents and pediatric patients with benign migratory glossitis.

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OBJECTIVE Benign migratory glossitis (BMG) is a disease that affects the tongue and is considered an inflammatory disorder well recognized. It is characterized by the appearance of erosive areas on the dorsum and lateral border of the tongue that can be isolated or multiple. The aim of this study

Iatrogenic Cushing's syndrome and topical steroid therapy: case series and review of the literature.

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Topical corticosteroids are considered first-line therapy in patients with chronic inflammatory oral mucosal diseases; among them, clobetasol propionate is one of the most widely used in oral medicine. Under physiological conditions, the transmucosal application is characterized by a significantly

Cronkhite-Canada syndrome polyps infiltrated with IgG4-positive plasma cells.

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Cronkhite-Canada syndrome (CCS) is a rare but serious protein-losing enteropathy, but little is known about the mechanism. Further more, misdiagnosis is common due to non-familiarity of its clinical manifestation. A 40-year-old male patient was admitted to our hospital because of diarrhea and

The neurological insights of the emerging coronaviruses

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Emerging Viral diseases are incredibly infectious and proficient in inducing pandemics. Unlike the previous emerging coronaviruses (ECoVs) which neurological complexities were uncommon, with neurological features exhibition at 14-25 days post-onset, yet with critical outcomes exhibiting >50%

Happy Hypoxemia in COVID-19-A Neural Hypothesis

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Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the clinical manifestations of the disease, we are

Clinical neurophysiology and cerebrospinal liquor analysis to detect Guillain Barré syndrome and polyneuritis cranialis in COVID-19 patients: a case series

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We report a case series of 5 patients affected by SARS-CoV-2 who developed neurological symptoms, mainly expressing as polyradiculoneuritis and cranial polyneuritis in the two months of COVID-19 pandemic in a city in the north east of Italy. A diagnosis of Guillain Barré syndrome was made on the

Transient hemiageusia in cerebrovascular lateral pontine lesions.

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Knowledge of human central taste pathways is largely based on textbook (anatomical dissections) and animal (electrophysiology in vivo) data. It is only recently that further functional insight into human central gustatory pathways has been achieved. Magnetic resonance imaging studies, especially

Taste responsiveness and diet preference in autoimmune MRL mice.

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One of the most profound behavioural deficits in lupus-prone MRL-lpr mice is blunted responsiveness to sweet solutions. Given the systemic nature of autoimmune/inflammatory disease, it was not clear whether impaired taste sensitivity or motivated response to palatable food underlie this deficit. The

A review of pathophysiology and neuropsychiatric manifestations of COVID-19

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Introduction: The outbreak of coronavirus disease 2019 (COVID-19) has become one of the most serious pandemics of the recent times. Since this pandemic began, there have been numerous reports about the COVID-19 involvement of the nervous

Neurological symptoms as a clinical manifestation of COVID-19: implications for internists

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Many experimental and clinical studies have proven that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has tropism to the nervous system. The infection of the nervous system by SARS-CoV-2 can occur via the nasal route through trans-synaptic pathways. Coronaviruses can infect

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