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Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome

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A prospective, non-randomized controlled open trial in psoriasis patients with metabolic syndrome was conducted between January 2019 and May 2020. Inclusion criteria were age ≥ 18 years, being affected by moderate to severe chronic plaque psoriasis and concomitant metabolic syndrome and being

Enhanced Liver Function in Non-alcoholic Obese Fatty Liver Patients by Low Level Laser Therapy

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Non-alcoholic fatty liver disease (NAFLD) is a very common disorder and refers to a group of conditions where there is accumulation of excess fat in the liver of people who drink little or no alcohol. The most common form of NAFLD is a non serious condition called fatty liver. NAFLD is part of the

Bariatric Surgery Effect Nonalcoholic Fatty Liver Disease

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Studying the Effect of Mediterranean Diet on Insulin Resistance Among Obese Children and Adolescents

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This Experimental clinical trial study will be conducted in Amman, the capital of Jordan to compare the effect of Mediterranean diet and regular diet on insulin resistance among 50 participants of obese children and adolescents (between 10 and 16 years of age) who are diagnosed with insulin

The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance

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AIMS OF STUDY The aim of this study is to investigate whether ingestion of curcumin will prevent hepatic insulin resistance (assessed by homeostatic model assessment of insulin resistance (HOMA-IR)) induced by short-term oral glucocorticoid (prednisolone) administration in overweight and obese

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis

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Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) are conditions without symptoms where inflammation in the liver can progress to end-stage liver disease (cirrhosis). Current standard of care for these conditions include control of metabolic syndrome which includes

Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes

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There has been a surge in incidence of the metabolic syndrome; a cluster of conditions which increase the risk of, type 2 diabetes (T2D) (90% of diabetes cases), non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), cardiovascular disease (including ischaemic heart disease

Alcohol Metabolism After Sleeve Gastrectomy

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The sample size was selected based on the number of obese patients who underwent SG at our Bariatric Center of Excellence IFSO-EC over the last 12 months, and the end-time of evaluation was estimated independently due to the lack of high evidence-based studies, such as randomized trials or

Probiotics in Metformin Intolerant Patients With Type 2 Diabetes

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The optimal daily dose of metformin is thought to be 2000 mg, however patients with metformin intolerance cannot reach this target dose. Participate in this study are metformin intolerant. Metformin intolerant patients have been defined as those not able to be treated with the metformin daily dose

Effect of a Very Low-Calorie Ketogenic Diet on Gut Microbiota and Fat Distribution

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Short-term interventions that use very low-calorie ketogenic diets and meal replacements may be prescribed for selected overweight or obese patients with type 2 diabetes or prediabetes. Few, inconsistent data are available on protein intake from various sources on body weight, the composition of gut

Alternate Day Fasting Combined and NAFLD for the Treatment of Non-alcoholic Fatty Liver Disease (NAFLD)

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Background: Approximately 65% of obese individuals have non-alcoholic fatty liver disease (NAFLD), and this condition is strongly related to the development of insulin resistance and diabetes. Innovative lifestyle strategies to treat NAFLD are critically needed. Alternate day fasting (ADF) has been

Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention

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Obesity is associated with different chronic disorders such as metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) and diabetes mellitus type 2 (DM2). It can be classified into mild, moderate and severe using different cut-off values of body mass index (BMI). Many interventions and

Glucose, Brain and Microbiota

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Subjects and methods: A. Cross-sectional study: Patients with obesity previously scheduled at the Service of Endocrinology, Diabetes and Nutrition (UDEN) of the Hospital "Dr. Josep Trueta" of Girona (Spain) will be recruited and studied. Subjects without obesity will also be recruited through a

The Effect of Curcumin on Liver Fat Content in Obese Subjects

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The prevalence of obesity is increasing worldwide. Obesity and its associated complications represent an enormous burden for obese individuals, their families, healthcare systems and societies. Non-alcoholic fatty liver disease (NAFLD) has emerged as a frequent and serious complication of obesity.

Evaluation of a Supplement for Weight Management in Obese and Overweight Individuals

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The present study is a randomized double-blind placebo controlled repeated measures design, with sampling of the cohorts on five separate occasions. Group 1: Intervention Group (n = 24) Healthy, overweight or obese physically inactive males, supplement, n = 12 Healthy, overweight or obese physically
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