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Sida 1 från 1991 resultat
Prevalence of hypoxemia among children with sickle cell anemia during steady state and crises: a cross-sectional study.
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BACKGROUND
Patients with sickle cell anemia (SCA) are prone to recurrent pain crises related to red blood cell sickling and vaso-occlusion with subsequent tissue hypoxia. Alveolar hypoxia has been shown to be associated with entrapment of sickle cells in the pulmonary microcirculation which may
Cardiovascular responses to hypoxia and anaemia in the toad Bufo marinus.
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Amphibians exhibit cardiorespiratory responses to hypoxia and, although several oxygen-sensitive chemoreceptor sites have been identified, the specific oxygen stimulus that triggers these responses remains controversial. This study investigates whether the cardiovascular response to oxygen shortage
Renal and placental secretion of erythropoietin during anemia or hypoxia in the ovine fetus.
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OBJECTIVE
The source of the erythropoietin (EPO) that circulates in the fetus is unknown although it is known that EPO does not cross the placenta and that fetal kidneys, liver, and placenta express the EPO gene. This study tested to what extent in vivo EPO secretion by the fetal kidneys and
Cerebral adaptations to chronic anemia in a model of erythropoietin-deficient mice exposed to hypoxia.
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Anemia and hypoxia in rats result in an increase in factors potentially involved in cerebral angiogenesis. Therefore, the aim of this study was to assess the effect of chronic anemia and/or chronic hypoxia on cerebral cellular responses and angiogenesis in wild-type and anemic transgenic mice. These
RADIOACTIVE IRON ABSORPTION BY GASTRO-INTESTINAL TRACT : INFLUENCE OF ANEMIA, ANOXIA, AND ANTECEDENT FEEDING DISTRIBUTION IN GROWING DOGS.
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Iron absorption is a function of the gastro-intestinal mucosal epithelium. The normal non-anemic dog absorbs little iron but chronic anemia due to blood loss brings about considerable absorption-perhaps 5 to 15 times normal. In general the same differences are observed in man (1). Sudden change from
Abnormal autonomic cardiac response to transient hypoxia in sickle cell anemia.
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The objective of this study was to non-invasively assess cardiac autonomic control in subjects with sickle cell anemia (SCA) by tracking the changes in heart rate variability (HRV) that occur following brief exposure to a hypoxic stimulus. Five African-American SCA patients and seven healthy control
Anemia is associated with metabolic distress and brain tissue hypoxia after subarachnoid hemorrhage.
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BACKGROUND
Anemia is frequently encountered in critically ill patients and adversely affects cerebral oxygen delivery and brain tissue oxygen (PbtO2). The objective of this study is to assess whether there is an association between anemia and metabolic distress or brain tissue hypoxia in patients
[The effect of hypoxia due to iron-deficiency anemia on the physicochemical properties of biological membranes].
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The lipid structure and Ca2+ permeability of red blood cell, hepatocyte and cardiomyocyte membranes were determined while investigating the effect of hypoxia caused by iron deficiency anemia upon the structural and functional state of biological membranes. The lipid composition and barrier
Chronic anemia in the newborn lamb: cardiovascular adaptations and comparison to chronic hypoxemia.
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The cardiovascular adaptations to chronic anemia were studied in the newborn lamb and then compared with the adaptations to chronic hypoxemia. Eight chronically instrumented newborn lambs underwent repeat isovolemic exchange transfusions to maintain their Hb concentrations at 60% of normal for age.
[Hypobaric hypoxia in the treatment of chronic anemia].
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The article studies the possibilities of adaptation for hypoxia in the conditions of decompressive barochamber for treatment of patients with asiderotic anemia. The high efficiency of hypobaric hypoxia was marked in treatment of these patients in medical stationary and during pre-operational
Dobutamine, a β1 Adrenoceptor Agonist, Increases Cerebral Oxygenation During Acute Anemia and Apneic Hypoxia.
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BACKGROUND
β1 blockers increase the risk of cerebral hypoxia during acute anemia and apneic hypoxia. We hypothesized that β1 stimulants conversely increase cerebral tolerance to anemia and hypoxia.
METHODS
After induction with isoflurane, twelve swine (mean ± SD: 25.2 ± 0.6 kg) received 200 µg kg-1
The effect of anemia on the ventilatory response to transient and steady-state hypoxia.
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The effects of anemia upon the ventilatory responses to transient and steady-state hypoxia were studied in unanesthetized goats. Responses to transient hypoxia (inhalation of several breaths of nitrogen) were considered to reflect peripheral chemoreceptor and non-chemoreceptor influences of hypoxia
Differential HIF and NOS responses to acute anemia: defining organ-specific hemoglobin thresholds for tissue hypoxia.
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Tissue hypoxia likely contributes to anemia-induced organ injury and mortality. Severe anemia activates hypoxia-inducible factor (HIF) signaling by hypoxic- and neuronal nitric oxide (NO) synthase- (nNOS) dependent mechanisms. However, organ-specific hemoglobin (Hb) thresholds for increased HIF
Association between hypoxemia and anemia following arthroplasty: A pilot clinical study.
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Hypoxia and anemia are common complications following joint arthroplasty. Whether hypoxia indicates that a patient is anemic and whether anemia causes a decline in arterial oxygen pressure accompanied by hypoxemia are not completely understood. The aim of the present study was to determine the
[The dynamic detection of cytokins under aplastic anemia and idiopathic thrombocytopenic purpura in the process of impact of hypoxic hypoxia].
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The natural hypoxic hypoxia enhances the synthesis processes and decrease the concentration balance in cytokine rets in patients with depression of hematopoiesis. It is established that the patients with aplastic anemia and idiopathic thrombocytopenic purpura, in contrast with patients with acute
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