8 resultat
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
BACKGROUND OF THE INVENTION
Release of such cytokines as tumor necrosis factor a (TNF-.alpha.) and transforming growth factor .alpha. (TGF-.alpha.) can cause adverse reactions ranging from psoriasis to sepsis. Many of these reactions are related to inflammation or autoimmune conditions, such as
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
The subject of the present invention is new O-substituted derivatives of (+)-cyanidan-3-ol, especially 3-O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the formula I ##STR2## in which R represents an optionally substituted hydrocarbon radical; an acyl radical of an organic
The subject of the present invention is new O-substituted derivatives of (+)-cyanidan-3-ol, especially 3-O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the formula I ##STR2## in which R represents an optionally substituted hydrocarbon radical; an acyl radical of an organic
This is a continuation-in-part of International Application PCT/GB95/00111, with an international filing date of Jan. 20, 1995.
The present invention relates to therapeutically active hydroxamic acid and carboxylic acid derivatives, to processes for their preparation, to pharmaceutical compositions
The present invention relates to therapeutically active hydroxamic acid and carboxylic acid derivatives, to processes for their preparation, to pharmaceutical compositions containing them, and to the use of such compounds in medicine. In particular, the compounds are inhibitors of metalloproteinases