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carboxylic acid/neoplasms

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Sida 1 från 197 resultat

Treatment of tumors with thiazolidine-4-carboxylic acid

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FIELD OF THE INVENTION This invention relates to chemotherapeutic methods for treating malignant tumors or other cancerous conditions. BACKGROUND The volume of research directed towards understanding the causes and finding a cure for cancer has greatly increased in the last ten years as a result of

Benzothienobenzacridine-7-carboxylic acids as cancer chemotherapeutic agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to tumor inhibiting pharmaceutical compositions, methods of inhibiting the growth of mammalian tumors, and 3-phenyl-5,6-dihydrobenz[c]acridine-6-carbosylic acids and derivatives thereof useful in such compositions and

3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to tumor inhibiting pharmaceutical compositions, methods of inhibiting the growth of mammalian tumors, and 3-phenyl-5,6-dihydrobenz[c]acridine-6-carboxylic acids and derivatives thereof useful in such compositions and
FIELD AND BACKGROUND OF THE INVENTION The present invention, in some embodiments thereof, relates to compounds, compositions and methods for treating disorders associated with pathological hyperplasia, metaplasia, dysplasia and neoplasia (oncoplasia) tissues, such as, for example, skin and visible
FIELD OF THE INVENTION The present invention relates to the use of a retinoid having unique properties for the treatment or prevention of breast cancer or leukemia. More specifically, the present invention relates to the use of 6-[3-[1adamantyl]-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN)
1. FIELD Provided herein are methods for treating, preventing or managing cancer, including specific leukemias by administering enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-ox- o-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid, which is also known
FIELD OF THE INVENTION The present invention relates to novel thiazolidinone amides, novel thiazolidine carboxylic acid amides, methods of making these compounds, and uses thereof, particularly for treating various cancers including but not limited to prostate, breast, ovarian, and skin

3-(2-hydroxy-phenyl)-1H-pyrazole-4-carboxylic acid amide derivatives as HSP90 inhibitors for the treatment of cancer

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This application is a U.S. National Stage application of co-pending PCT application PCT/GB2003/005275, filed Dec. 4, 2003, which claims the priority of Great Britain Patent Application No. 0228417.2, filed Dec. 5, 2002. These applications are incorporated herein by reference in their

Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers

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FIELD OF THE INVENTION This application is divisional application under 35 U.S.C. .sctn.120 of U.S. Ser. No. 13/063,445, now U.S. Pat. No. 8,569,466, which was the U.S. national phase entry under the provisions of 35 U.S.C. .sctn.371 of International Patent Application No. PCT/US09/56515 filed Sep.

Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers

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FIELD OF THE INVENTION The present invention relates to aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including ulcerative colitis and colon cancer, as well as to therapeutic compositions comprising such derivatives, and methods of treatment and

Carboxylic acid derivatives, their preparation and use in treating cancer

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BACKGROUND Cancer is a disease for which many potentially effective treatments are available. However, due to the prevalence of cancers of various types and the serious effects cancer can have, more effective treatments, especially those with fewer adverse side effects than currently available forms

Methods of cancer treatment with 2-(1'H-Indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester

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TECHNICAL FIELD The presently disclosed invention relates to a method of cancer treatment using 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester ("ITE") or one of its structural analogs. More particularly, the present invention provides a method by administering a therapeutically

Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity

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BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to axial hydroxy and axial carboxylate platinum (IV) compounds which possess antitumor activity. Certain of the compounds of the present invention also possess excellent water-solubility which makes them more efficacious in

Carboxylic acid derivatives and pharmaceutical agent comprising the same as active ingredient

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TECHNICAL FIELD The present invention relates to carboxylic acid derivatives. More specifically, the present invention relates to a carboxylic acid derivative of formula (I) ##STR00002## wherein all symbols have the same meanings as described below; a non-toxic salt thereof and a pharmaceutical

Phenylquinazolinecarboxylic acids and derivatives as cancer chemotherapeutic agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to quinazoline-4-carboxylic acids, processes for preparing them, pharmaceutical compositions containing them and methods of using them as cancer chemotherapeutic agents. 2. Literature Background Only a small number of
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