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Functionally Validated Structural Endpoints for Early AMD
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The Alabama Study on Early Age-Related Macular Degeneration 2 (ALSTAR2) is a prospective cohort study with baseline measurements that are repeated at follow-up 3 years later. The baseline and 3 year follow-up visits will each consist of 2 visits for a total of 4 visits.
Study assessments are listed
Macular Pigment and Visual Performance in Glaucoma Patients
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Neurodegeneration of the optic nerve and associated ganglion cell death in glaucoma leads to several well-characterized losses in visual function, most notably progressive peripheral visual field loss. Several recent studies have characterized significant visual function deficits in glaucoma
Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)
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Seaweed Extract Supplementation and Metabolic Biomarkers
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Diabetes melitus is a group of metabolic disorders resulting from a defect in insulin production and/or insulin action. The World Health Organisation (WHO) has estimated that the total number of people with diabetes mellitus worldwide will increase from 171 million in 2000 to nearly 370 million in
Bioavailability of Phytonutrients From Novel Preparations of Broccoli
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Consumption of Brassica vegetables (which include broccoli, cabbage, and kale) is inversely associated with the incidence of several cancers, including cancers of the lung, stomach, liver, colon, rectum, breast, endometrium, and ovaries. Brassica vegetables are a good source of many nutrients
MORINGA; Delivering Nutrition and Economic Value to the People of Malawi
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Lack of adequate nutrition remains the world's most prevalent health problem and the single biggest contributor to child mortality. It is a direct or indirect cause of 43% deaths worldwide among children under 5 years of age. The two separate forms of malnutrition - wasting (a deficit in weight
Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men
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Consumption of foods containing the carotenoids lutein, lycopene, beta-carotene, as well as vitamin E, have been associated with lower risk of developing chronic diseases including cardiovascular disease, cancer, age related macular degeneration, and cognitive decline. While the parent compounds
Wenzhou Dry Age-related Macular Degeneration (AMD) Progression Study
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Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly.[1] The disease is categorized into early, intermediate, or advanced stages based on the severity of symptoms. The advanced stage, including GA and CNV, involves central region of the retina, which leads to a
The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular Degeneration
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While being benefited from the results of previous studies, the sample size of the research was type 1 error performance α=0.05 and type 2 error performance β=0.20. The power of the test was taken as 1-β=0.80 and the power analysis was statistically made with NCCS PAS 11 program. 200 individuals
Macular Pigment Measurements in Eye & Other Tissues
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The macula of the human retina (the structure responsible for high acuity vision essential for reading, driving and recognizing faces) is colored an intense yellow due to the deposition of two carotenoid compounds, lutein and zeaxanthin. These xanthophyll carotenoids are derived exclusively from the
Impact of Egg Consumption on Carotenoid and Vitamin D Bioavailability in Pre- and Post-menopausal Women
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The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily. However, US adults only consume on average 2.6 cups of fruits and vegetables daily. This low consumption may further result in the limited availability of fat soluble, health-promoting,
Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.
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Regional Kale as Source of Lutein and Zeaxanthin to Improve Vision of AMD-patients
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Carotenoid Supplementation and Normal Ocular Health
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It is believed that the macular pigment protects the retina against photooxidative damage which can lead to agerelated macular degeneration (AMD). It is also hypothesized to enhance visual performance in normal human eyes. Much of the research into lutein supplementation has been centered around AMD
Study of the Macular Pigment by the Consumption of Corn With Strong Content in Zeaxanthine
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The age macular degeneration represents the first cause of blindness in industrialized countries if it is not treated. In France, the AMD affects 600 000 persons and this figure should continue to increase, notably because of the increase of the life expectancy. The macula is responsible of the fine
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