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Sida 1 från 810 resultat
Placenta, embryo, and tumor uptake of 67Ga-citrate and 59Fe-citrate.
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The uptake of gallium citrate Ga67 and ferrous citrate Fe59 was studied in pregnant rats with or without a 4-dimethylamino-stilben(DS)-induced sarcoma tumor. The liver and placenta of the mother concentrated 67Ga, while the uptake of 67Ga in the embryo was minimal. However, the embryo showed higher
[Thermo- and scintigraphy with 67Ga citrate in the diagnosis of oro- and parapharyngeal tumors].
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The authors analyzed the results of thermographic and scintigraphic (using 67Ga-citrate produced in the USSR) investigations in 41 patients: 10 with tumors of the oral cavity, 12 with oropharyngeal tumors, and 19 with parapharyngeal tumors. Of the latter 10 had morphologically verified benign
Uptake and excretion of 67Ga-citrate in malignant tumors and normal cells.
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Using in vivo and in vitro experimental models, the uptake and excretion of 67Ga-citrate in tumor cells and normal cells were studied. The time-lapse accumulation of 67Ga in the tumor of rats bearing Yoshida sarcoma reached its peak 24 h after the administration of 67Ga and gradually decreased
Accumulation of radioisotopes with tumor affinity. I. Uptake and excretion of 67Ga-citrate in malignant tumors and normal cells.
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Using in vivo and in vitro experimental models, the uptake and excretion of 67Ga-citrate in tumor cells and normal cells were studied. The time-lapse accumulation of 67Ga in the tumor of rats bearing Yoshida sarcoma reached its peak 24 h after the administration of 67Ga and gradually decreased
Clinical evaluation of tumor scanning with 169-Yb-citrate.
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169-Yb-citrate was used as the tumor-scanning agent in 360 patients with malignant tumors and in 55 others with benign lesions and the results compared with 67-Ga-citrate studies in other series. In malignant tumors, the overall positive detection rate for ytterbium was 65.3%; in benign lesions, the
A Feasibility Study Showing [68Ga]Citrate PET Detects Prostate Cancer.
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The management of advanced or recurrent prostate cancer is limited in part by the lack of effective imaging agents. Metabolic changes in prostate cancer have previously been exploited for imaging, culminating in the recent US FDA approval of [11C]choline for the detection of subclinical recurrent
A clinical comparison of the tumour-imaging radiopharmaceuticals 67Gallium-citrate and 111Indium-labelled bleomycin.
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Two tumour-imaging agents, 67Gallium-citrate and 111Indium-bleomycin have been assessed in a clinical trial. Both the quality of tumour image and correlation with known sites of disease has been compared by scanning with the two agents in a variety of malignant diseases. In addition, comparative
Technetium-99m stannous citrate brain-tumor uptake in mice: concise communication.
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The pharmacodynamics of technetium-99m stannous citrate were studies in Yale-Swiss mice bearing a sarcoma-like transplantable brain tumor, and the renal kinetics were determined in normal mice. Using a rating system based on tumor uptake and tumor-to-brain, tumor-to-blood, and tumor-to-skin ratios,
[103Ru for tumor scanning--a comparative study on tissue distributions of 103Ru-chloride and 103Ru-citrate in tumor-bearing animals (author's transl)].
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Biological distribution of 103Ru in mice bearing Ehlrich's solid tumor and rats bearing AH-130 solid tumor were studied with two compounds of 103Ru, the chloride and citrate. The radioactivity of 103Ru-chloride showed slower excretion and higher tumor concentration than that of citrate. The
Sufentanil citrate and morphine/bupivacaine as alternative agents in chronic epidural infusions for intractable non-cancer pain.
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Intraspinal narcotic (usually intrathecal morphine) infusions with implanted pumps are increasingly used in patients with intractable chronic pain not caused by cancer. In some patients, pain control is difficult with infusions of morphine. Seven patients with diagnoses of arachnoiditis, epidural
Comparison of radiolabeled bleomycins and gallium citrate in tumor-bearing mice.
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Radioiodinated bleomycin is a chemically stable radiopharmaceutical that can be prepared with high specific activity using 123I. Its pharmacokinetics were compared with those of 99mTc,- 111In-, and 57Co-bleomycin, and 67Ga citrate in mice bearing a transplanted KHJJ tumor. The in vivo kinetics and
Comparison of oncophilic radiopharmaceuticals, *I-fibrinogen, 67Ga-citrate, 111In-bleomycin, and *I-bleomycin in tumor-bearing mice.
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The pharmacokinetics of 67Ga-citrate, 111In-bleomycin, *I-bleomycin, and *I-fibrinogen were compared in a murine KHJJ tumor model in order to assess their relative potential as agents for in vivo detection of cancer. Although all four agents have been reported to be clinically efficacious, in this
Breast cancer in a man treated effectively with a large dose of tamoxifen citrate.
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Breast cancer in males is comparatively rare. A 41-year-old man visited our hospital with a complaint of left breast tumor. Initial examination showed remarkably diffuse metastatic lesions in the lung field and small metastatic lesions in the surrounding skin. Modified radical mastectomy, including
[Efficacy of a fentanyl citrate buccal tablet for esophageal cancer pain management in a patient unable to take oral medication].
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We report a case ofa 60-year old male esophageal cancer patient who was unable to take oral medication, but was successfully treated using a fentanyl citrate buccal tablet. The patient survived a suicide attempt as a youth in which he ingested poison, but was left with a stricture of the esophagus.
Gallium-67 citrate uptake by cultured tumor cells, stimulated by serum transferrin.
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The uptake of the tumor scanning agent 67-Ga citrate by cultured mouse tumor cells wqs greatly enhanced with small additons of certain sera to the culture medium. This stimulation of uptake was due to a macromolecular serum component, provisionally identified with transferrin. The response under
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