Colitis / feber

Artemisinin with berberine compositions and methods of making

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FIELD OF INVENTION The present invention relates generally to novel therapeutic compositions, and more specifically to herbal compositions and methods of making and combining artemisinin and berberine to deliver active therapeutic substances for treatment and prevention of diseases and infections

Artemisinin with berberine compositions and methods of making

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FIELD OF INVENTION The present invention relates generally to novel therapeutic compositions, and more specifically to herbal compositions and methods of making and combining artemisinin and berberine to deliver active therapeutic substances for treatment and prevention of diseases and infections

Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity

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TECHNICAL FIELD The present invention is directed to certain isoxazolone compounds that inhibit the release of inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor (TNF) from cells. The compounds of the invention, therefore, are useful in treating diseases involving unwanted

Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity

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TECHNICAL FIELD The present invention is directed to certain isoxazolone compounds that inhibit the release of inflammatory cytokines such as interleukin-1 (1L-1) and tumor necrosis factor (TNF) from cells. The compounds of the invention, therefore, are useful in treating diseases involving unwanted

Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and TACE inhibitors

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FIELD OF INVENTION This invention relates to allenic aryl sulfonamide hydroxamic acids which act as inhibitors of TNF-.alpha. converting enzyme (TACE) and matrix metalloproteinase (MMP). The compounds of the present invention are useful in disease conditions mediated by MMP and TACE, such as

Pyrimidine compounds and their uses

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FIELD Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. ##STR00002## The present invention also

Pyrimidine compounds and their uses

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FIELD Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. ##STR00002## The present invention also

Heterocycles

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FIELD Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. The present invention more particularly

Substituted heterocyclic compounds and methods of use

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BACKGROUND OF THE INVENTION The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the

Substituted heterocyclic compounds and methods of use

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BACKGROUND OF THE INVENTION The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the

Pyrimidine carboxamides

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FIELD OF THE INVENTION The present invention relates to novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their

Substituted heterocyclic compounds and methods of use

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BACKGROUND OF THE INVENTION The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the

Substituted heterocyclic compounds and methods of use

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the

Substituted heterocyclic compounds and methods of use

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION The present invention comprises a new class of compounds useful in treating diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the

colitis/feber

Artemisinin with berberine compositions and methods of making

Artemisinin with berberine compositions and methods of making

Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity

Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity

Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and TACE inhibitors

Pyrimidine compounds and their uses

Pyrimidine compounds and their uses

Heterocycles

Substituted heterocyclic compounds and methods of use

Substituted heterocyclic compounds and methods of use

Pyrimidine carboxamides

Substituted heterocyclic compounds and methods of use

Substituted heterocyclic compounds and methods of use

Substituted heterocyclic compounds and methods of use

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