congenital hypothyroidism/kalium

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Different aspects of kidney function in well-controlled congenital hypothyroidism.

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OBJECTIVE Congenital hypothyroidism (CH) increases the prevalence of kidney and urogenital malformations. There are limited studies considering different aspects of kidney function in well-controlled CH patients. We evaluated some features of kidney function in euthyroid children with CH who have

Congenital hypothyroidism from complete iodide transport defect: long-term evolution with iodide treatment.

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Hypothyroidism from iodide transport deficiency is a rare disease, especially when found in two affected siblings. Treatment with high doses of iodide has been recommended, but no long term results have been reported. Two siblings with congenital hypothyroidism due to total failure to transport

Congenital hypothyroidism: etiology.

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The etiology of congenital hypothyroidism (CH) is important in determining its severity, prognosis, genetic counseling and clinical management. OBJECTIVE investigate the causes of CH and their severity using serum levels of FreeT4 and TSH. METHODS 243 neonates with CH (61% were girls) diagnosed by

[Evaluation of potassium iodide in Polish dietary salt].

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The consequences of iodine deficiency occurring still in Poland include serious health disorders in the population, such as psycho- somatic retardation, hypothyroidism, endemic goitre, even cretinism. Administration of iodized edible salt with daily diet is an effective method for prevention of

Diagnostic re-evaluation of children with congenital hypothyroidism.

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OBJECTIVE To investigate the causes of congenital hypothyroidism in children more than 3 years of age and to document the frequency of transient vs permanent hypothyroidism. METHODS Hospital based observational study. METHODS Pediatric endocrine clinic of a medical college. METHODS Children over 3

[Thyroid diseases in sub-Saharan Africa].

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Thyroid gland diseases vary according to the environment. In sub-Saharan Africa, they are also influenced by population isolation and the absence of food self-sufficiency, both factors affecting the onset and persistence of iodine-deficiency goiters. More cosmopolitan diseases are now added to these

The distribution patterns of trace elements in the brain and erythrocytes in a rat experimental model of iodine deficiency.

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Cretinism is a disease characterized by neurological defects associated with severe iodine deficiency. In a rat model of severe iodine deficiency, we investigated the distribution pattern of trace elements (iodine [I], selenium [Se], and bromine [Br] in brain tissue samples; potassium [K], calcium

Factors determining the differential tissue response of Na/K-ATPase to thyroid hormone in the neonatal rat.

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The concentration of ouabain binding sites (OBS), a measure of the abundance of sodium/potassium-dependent ATPase (Na/K-ATPase), was measured in cerebral cortex (CC), cerebellum (CBL), brown adipose tissue (BAT), and heart of neonatal rats with congenital hypothyroidism. In euthyroid rats, the

Five cases of absence of iodide concentrating mechanism.

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Five cases, 2 males and 3 females, with absence of iodide concentrating mechanism are reported. Three of the five subjects are siblings and the eldest sister has no symptom to account for the cretinism. All 5 cases have improved clinically following the administration of potassium iodide and 4 cases

An environmental approach to correcting iodine deficiency: supplementing iodine in soil by iodination of irrigation water in remote areas.

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OBJECTIVE Iodine deficiency disorders continue to be a severe problem in many parts of Central Asia, causing delayed mental development and cretinism in indigenous populations. In some areas, iodized salt has not succeeded in controlling this problem. In southern Xinjiang Province of China, we tried

[Should the iodination of table salt be increased in Austria?].

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Since the main reason of endemic goiter is the avoidable iodine deficiency, this in an unnecessary disease. In Austria an exemplary iodized salt prophylaxis was introduced in 1963. Thanks to this iodized salt prophylaxis endemic cretinism has died out. The incidence of hypothyroidism in newborns is

Iodination of irrigation water as a method of supplying iodine to a severely iodine-deficient population in Xinjiang, China.

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Severe iodine deficiency still occurs in many countries, and causes cretinism and mental impairment. In southern Xinjiang province, China, after usual methods of iodine supplementation had failed, we iodinated irrigation water to increase iodine in soil, crops, animals, and human beings. 5%

Iodine deficiency disorders in South Africa.

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Iodine is an essential micronutrient, but iodine deficiency remains common worldwide, including many African countries. In South Africa endemic goitre was first noted in the 1920s. Several subsequent surveys have indicated its widespread persistence, despite the limited availability of iodised salt.

Population living in the Red Sea State of Sudan may need urgent intervention to correct the excess dietary iodine intake.

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BACKGROUND Both inadequate and high intakes of iodine are associated with thyroid disease and associated abnormalities. Consumption of foods deficient in iodine induces hypothyroidism. Conversely, excessive intake of the nutrient precipitates hyperthyroidism. Iodine deficiency causes impairment of

History of endemic goiter in Croatia: from severe iodine deficiency to iodine sufficiency.

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At the time after the Second World War, endemic goiter was present in most parts of Croatia with a prevalence of more than 50% and presence of cretinism. In the village of Rude near Zagreb, goiter was detected in 85% of school children with 2.3% of cretins in the village population. In 1953 the

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