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Sida 1 från 118 resultat
Treatment of obesity, the metabolic syndrome, type 2 diabetes, cardiovascular diseases, dementia, alzheimer's disease and inflammatory bowel disease by using at least one bacterial strain from Prevotella
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FIELD OF INVENTION
A product for use in the treatment of obesity, the metabolic syndrome, type 2 diabetes, cardiovascular diseases, dementia, alzheimers disease and inflammatory bowel disease comprising at least one isolated bacterial strain from the species Prevotellaceae, herein the strain is
Compositions and methods for utilization of algal compounds
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BACKGROUND OF THE INVENTION
Field of the Invention
This invention relates to algal biochemistry, and more specifically, to algal compositions and methods of utilization.
SUMMARY OF THE INVENTION
Provided herein are exemplary products for mammalian consumption selected from any of a composition
Phenylpyrrole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2012/081744 filed Dec. 7, 2012, claiming priority based on Japanese Patent Application No. 2011-268561 filed Dec. 8, 2011, the contents of all of which are incorporated herein by
Compound with agitation effect on peroxisome proliferator-activated receptor process for its preparation and use thereof
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RELATED APPLICATIONS
The instant application is the U.S. National Phase under 35 U.S.C. .sctn.371 of International Application No. PCT/CN2009/073140 entitled COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR .delta., AND PREPARATION METHOD AND USE THEREOF, filed Aug. 7,
Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient
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TECHNICAL FIELD
The present invention relates to a nitrogen-containing bicyclic compound or a pharmacologically acceptable salt thereof and a pharmaceutical composition comprising it as active ingredient.
More specifically, the present invention relates to (1) a compound of formula (I)
##STR00002##
Substituted benzopyrans as selective estrogen receptor-beta agonists
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BACKGROUND OF THE INVENTION
The present invention relates to novel benzopyran ER-.beta. agonist compounds, pharmaceutical compositions thereof, and use of these compounds to treat a ER-.beta. mediated disease such as benign prostatic hypertrophy, obesity, dementia, hypertension, incontinence, colon
Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
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FIELD OF THE INVENTION
The present invention relates to a novel treatment of low total androgens accompanied by one or more symptoms classically attributed to male hypogonadism or low testosterone. The number of individuals over 65 years of age has increased more than 10-fold compared with the 1990s
Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
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FIELD OF THE INVENTION
The present invention relates to a novel treatment of low total androgens accompanied by one or more symptoms classically attributed to male hypogonadism or low testosterone. The number of individuals over 65 years of age has increased more than 10-fold compared with the 1990s
Piperidine derivative compounds and drugs containing the compounds as the active ingredient
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TECHNICAL FIELD
The present invention relates to a piperidine derivative.
More specifically, the present invention relates to (1) a piperidine derivative of formula (I)
##STR00002## (2) a method for the preparation thereof, (3) a composition comprising it as an active ingredient, (4) a compound of
Amido-thiophene compounds and their use
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TECHNICAL FIELD
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain amido-thiophene compounds that, inter alia, inhibit 11.beta.-hydroxysteroid dehydrogenase type 1 (11.beta.-HSD1). The present invention also
Amido-thiophene compounds and their use
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TECHNICAL FIELD
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain amido-thiophene compounds that, inter alia, inhibit 11.beta.-hydroxysteroid dehydrogenase type 1 (11.beta.-HSD1). The present invention also
Amido-thiophene compounds and their use as 11-beta-HSD1 inhibitors
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TECHNICAL FIELD
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain amido-thiophene compounds that, inter alia, inhibit 11.beta.-hydroxysteroid dehydrogenase type 1 (11.beta.-HSD1). The present invention also
25-hydroxyvitamin D3 24-hydroylase transgenic rats
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TECHNICAL FIELD
This invention relates to 25-hydroxyvitamin D.sub.3 24-hydroxylase transgenic animals.
BACKGROUND ART
The transgenic animal carries a gene introduced to its own or progenitor's germ cell line in an early stage of development (usually, single cells).
Wagner et al. (1981, ProNAS, USA,
(4-phenyl-piperidin-1-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds and their use
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TECHNICAL FIELD
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain (4-phenyl-piperidin-1-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds that, inter alfa, inhibit 11.beta.-hydroxysteroid
3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1H-pyrazol-4-yl)-thio- phen-3-yl]-methanones as inhibitors of 11 (.beta.)-HSD1
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TECHNICAL FIELD
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1H-pyrazol-4-yl)-thi- ophen-3-yl]-methanone,
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