ergometrine/seizures

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Ergometrine administration for post-partum haemorrhage in an undiagnosed pre-eclamptic.

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We report a case of a parturient who was well antenatally but presented with oliguria following delivery. The possibility of post-partum pre-eclampsia was obscured by simultaneous post-partum haemorrhage. Ergometrine was given and she suffered an eclamptic seizure shortly after. We discuss the

Overdose of ergometrine in the newborn infant: acute symptomatology and long-term outcome.

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OBJECTIVE To document the short- and long-term effects of accidental administration of ergometrine in adult dosage to the newborn infant. METHODS The case records of all infants admitted to the Royal Children's Hospital (RCH) since 1970 with a diagnosis of acute ergometrine overdose were reviewed,

Ergot alkaloids as dopamine agonists: comparison in two rodent models.

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A series of ergot alkaloids, together with the DA agonists apomorphine and piribedil, were tested for protective effects against audiogenic seizures in an inbred strain of mice (DBA/2) and for induction of circling behaviour in mice with unilateral destruction of one nigrostriatal DA pathway. The

Blockade of photically induced epilepsy by 'dopamine agonist' ergot alkaloids.

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The effect of the intravenous administration of ergot alkaloids on epileptic responses to intermittent photic stimulation )IPS) has been studied in adolescent baboons, Papio papio, from Senegal. Ergocornine, 1--2 mg/kg, produced marked autonomic and behavioural effects, slowed the EEG, and abolished

Accidental administration of Syntometrine in adult dosage to the newborn.

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The clinical course is described of an infant who accidentally received an adult dose of Syntometrine (synthetic oxytocin + ergometrine) at delivery. The infant soon became ill with convulsions and ventilatory failure, and later with water intoxication. Similar reported cases are reviewed and

Cardiac arrest during caesarean section.

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A case is described of a previously healthy obese woman in her fourth pregnancy who presented for caesarean section due to cephalopelvic disproportion (CPD). Forty minutes after a spinal anaesthetic a healthy child was delivered. Shortly after the injection of ergometrine and Syntocinon into the

Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.

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A method has been described for the study of the central effects produced by the intracerebral injection of drugs in the unanaesthetized mouse. The effects observed were in good agreement with those obtained after similar injections in cats, dogs and human beings. After intracerebral injection,

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