erythritol/nekros

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Biosurfactant mannosyl-erythritol lipid inhibits secretion of inflammatory mediators from RBL-2H3 cells.

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BACKGROUND Biosurfactant mannosyl-erythritol lipids (MELs) are glycolipids produced by microbes that have various biological activities. It has been reported that MELs exhibit excellent surface-activity and also various bioactivities, such as induction of cell differentiation and apoptosis. However,

Impaired biliary excretion of taurocholate associated with increased biliary tree permeability in mirex- or chlordecone-pretreated rats.

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Impaired biliary excretion of exogenously provided xenobiotic metabolites was demonstrated previously after pre-exposure of rats to mirex (MX) or chlordecone (CD). This toxicity was studied further in pentobarbital-anesthetized rats, cannulated at the common bile duct. We found reduced biliary

Hepatotoxicity of an HIV protease inhibitor in dogs and rats.

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Oral administration of the HIV protease inhibitor L-689,502 caused cholestasis and hepatocyte injury in rats and dogs. These changes occurred rapidly, with elevations in serum transaminase observed as early as 6 hr after oral dosing in dogs. The acute phase of this hepatotoxic response was

Disease of Floral Buds of Kiwifruit in Spain Caused by Pseudomonas syringae.

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In 1999 and 2000, decay of floral buds of Actinidia deliciosa was observed in plantations in the Principality of Asturias, Spain. Bud decay led to a decrease (up to 40%) in the production of kiwifruit. Floral buds with symptoms of browning and necrosis were collected from different areas

Temporal relationship of changes in hepatobiliary function and morphology in rats following alpha-naphthylisothiocyanate (ANIT) administration.

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These studies were designed to evaluate ANIT-induced changes in both hepatobiliary function and morphology during the onset, progression, and recovery of ANIT-induced cholestasis. A single oral dose of 150 mg/kg of ANIT or vehicle was administered by gavage to male Sprague-Dawley rats and

Erwinia persicina Causing Chlorosis and Necrotic Spots in Leaves and Tendrils of Pisum sativum in Southeastern Spain.

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In 2003, symptoms of generalized chlorosis as well as necrosis in leaves and tendrils were observed in Pisum sativum L. cv Tirabeque grown in green fields in southeastern Spain (Granada Province), and by 2004, the disease affected approximately 12 ha. Bacteria isolated from symptomatic samples were

Bacterial Leaf Spot of Cilantro in Florida.

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In the 1995 to 1996 winter vegetable season, a leaf spot disease of cilantro (fresh coriander) (Coriandrum sativum L.) was widespread throughout commercial plantings in the Everglades Agricultural Area south and east of Lake Okeechobee. Symptoms first appeared as water-soaked spots ≤1 mm in

Accumulation of a potent gammadelta T-cell stimulator after deletion of the lytB gene in Escherichia coli.

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Activation of human Vgamma9/Vdelta2 T cells by many pathogens depends on the presence of small phosphorylated non-peptide compounds derived from the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway of isoprenoid biosynthesis. We here demonstrate that in Escherichia coli mutants deficient in lytB,

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