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5 resultat
Inhibiting and disaggregating effect of gel-filtered Galega officinalis L. herbal extract on platelet aggregation.
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Logga in Bli medlem
The in vitro inhibiting and disaggregating effect on platelet aggregation of a gel-fractionated herbal extract from Galega officinalis L. is examined. The obtained Sephadex G-25 filtered fraction was 35-36 times more active than the crude extract. The threshold concentration at which this fraction
Anti-aggregation activity of crude water extract of Galega officinalis L. fractionated on Sephadex G-25 and Sepharose 4B.
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Logga in Bli medlem
The present study describes a method for preparation of biologically active fraction from crude water extract of Galega officinalis L. by gel filtration on Sephadex G-25 and Sepharose 4B. In an in vitro experiment (at a dose of 12.0 +/- 0.45 micrograms/ml) fractionated extracts inhibited adenosine
Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation.
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Logga in Bli medlem
A fraction from crude extract of Galega officinalis L. was purified by gel filtration on Sephadex G-25, Sepharose 4B, and ion-exchange chromatography on diethylaminoethyl (DEAE)-cellulose. The fraction with molecular weight 100-140 kDa appears to have a polysaccharide nature, including protein. The
Effect of metformin on the human T98G glioblastoma multiforme cell line.
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Logga in Bli medlem
Metformin is a guanidine derivative found in Galega officinalis that is commonly used to treat diabetes mellitus. The mechanism of action of metformin involves regulation of the adenosine monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathway, which is implicated in
Review of Biguanide (Metformin) Toxicity.
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Logga in Bli medlem
In the 1920s, guanidine, the active component of Galega officinalis, was shown to lower glucose levels and used to synthesize several antidiabetic compounds. Metformin (1,1 dimethylbiguanide) is the most well-known and currently the only marketed biguanide in the United States, United Kingdom,
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