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gestational weight gain/bröstcancer

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Pregnancy weight gain and premenopausal breast cancer risk.

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OBJECTIVE To investigate whether excessive weight gain during pregnancy alters a woman's risk of developing premenopausal breast cancer. METHODS We conducted a nested case-control study within a cohort composed of 22,610 Finnish women (mean age, 40; SD 6.4) who responded to a questionnaire

Pregnancy weight gain and breast cancer risk.

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BACKGROUND: Elevated pregnancy estrogen levels are associated with increased risk of developing breast cancer in mothers. We studied whether pregnancy weight gain that has been linked to high circulating estrogen levels, affects a mother's breast cancer risk. METHODS: Our cohort consisted of women

Maternal factors and breast cancer risk among young women.

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The results from previous studies have provided evidence to support the hypothesised association between intrauterine oestrogen exposure and subsequent risk of breast cancer. Information has not been available to study this relationship for several perinatal factors thought to be related to

Pregnancy weight gain is not associated with maternal or mixed umbilical cord estrogen and androgen concentrations.

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The association of maternal weight gain with serum hormone concentrations was explored in 75 women who had healthy, singleton pregnancies. Estradiol, estriol, estrone, androstenedione, testosterone, dehydroepiandrosterone (DHEA), and DHEA sulfate concentrations were measured both in maternal and

Mothers' pre-pregnancy BMI and weight gain during pregnancy and risk of breast cancer in daughters.

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Previous studies have established that higher birthweight is associated with increased risk of breast cancer. However, the mechanisms underlying this association remain unclear. We explored whether maternal pregnancy weight gain and pre-pregnancy body mass index (BMI), which influence birthweight,

Childbearing recency and modifiers of premenopausal breast cancer risk.

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The purpose of this study was to examine the risk of premenopausal breast cancer for women in relation to childbearing recency and whether this association differs by breast-feeding history and/or the amount of weight gained during pregnancy. This analysis was based on data from a population-based

Gestational biomarkers of daughter's breast cancer in the Child Health and Development Studies.

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We examined the link between gestational biomarkers and breast cancer in 9169 daughters born into the Child Health and Development Studies from 1959 to 1967. We identified 137 breast cancer cases diagnosed by age 52 as of 2012. Markers of increased risk included higher placental volume and rapid 2nd

Pregnancy characteristics and maternal risk of breast cancer.

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In a population-based case-control study of parous women less than 45 years of age, we evaluated the relations of various pregnancy characteristics to maternal breast cancer risk. Cases (N = 1,239) diagnosed with in situ or invasive breast cancer from 1990 to 1992 in Atlanta, GA, Seattle/Puget

Timing of dietary estrogenic exposures and breast cancer risk.

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The same dietary component, such as fat or phytochemicals in plant foods, can have an opposite effect on breast cancer risk if exposed in utero through a pregnant mother or at puberty. Dietary exposures during pregnancy often have similar effects on breast cancer risk among mothers and their female
BACKGROUND Elevated pregnancy hormone levels, such as oestrogen and progesterone, may increase the risk of developing breast cancer both in mothers and offspring. However, the reasons for large inter-individual variations in estrogen and progesterone levels during pregnancy remain unknown. The

Maternal and Infant Anthropometric Characteristics and Breast Cancer Incidence in the Daughter.

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The intrauterine and early life environments have been linked to the etiology of breast cancer in prior studies. We prospectively examined whether maternal and newborn anthropometric factors as reported by the mother are related to an increased incidence of adult breast cancer in the daughter. We

Maternal Anthropometry and Mammographic Density in Adult Daughters.

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OBJECTIVE We examined the relation between maternal anthropometry and mammographic density in the adult daughter using prospectively collected data. METHODS Our study included a total of 700 mother-daughter dyads participating in an adult follow-up of women born in 2 US birth cohorts: the Child

Maternal age, anthropometrics and pregnancy oestriol.

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It has been hypothesised that oestrogen exposure in utero influences the risk for breast cancer in adult life. Although several studies report associations between breast cancer and maternal factors associated with birthweight of the offspring - a marker for antenatal oestriol exposure - little is

Body size from birth through adolescence in relation to risk of benign breast disease in young women.

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Body size, from birth throughout adulthood, is associated with breast cancer risk, but few studies have investigated early-life body size and benign breast disease (BBD), a well-established breast cancer risk factor. We consider whether prenatal factors and size at birth, 10, 18 year, and

Factors influencing breast changes after pregnancy.

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Pregnancy and breastfeeding are major factors reducing breast cancer (BC) risk. A potential mechanism for this effect might be changes in mammographic density, but other factors might be involved. The aim of this study was to investigate factors influencing changes in breast size and breast
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