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The time course of the content of hexose fractions was compared with the size of the myocardial infarction appraised from the ECG and with the clinical course of the acute period of myocardial infarction in 100 patients. The degree and duration of the increase in the blood glucosaminoglycane content
A total of 136 patients with trans- and 200 with non-transmural myocardial infarction (MI) were examined over time for chlorine-soluble mucoprotein (MP), serum hexoses (SH), their fraction-hexoses of glycosaminoglycans (H-GAG), and hexoses of glycoproteins (H-GP), serum, plasma and urine
The effect of administration of carnitine on the severity of myocardial infarction in rats induced by isoproterenol was studied by following histopathological and biochemical parameters. Carnitine afforded partial protection against myocardial infarction. Serum aspartate amino transferase (GOT) and
A study of 20 patients with protracted myocardial infarction and 142 patients with transmural myocardial infarction showing a routine course revealed that the clinico-biochemical equivalent of prolonged course of reparative processes in protracted myocardial infarction are up to 2 months registered
The aim of this investigation was to evaluate the preventive role of morin, a flavonoid, on cardiac marker enzymes such as aspartate transaminase, lactate dehydrogenase, creatine kinase and creatine kinase-MB, membrane-bound enzymes such as sodium potassium-dependent adenosine triphosphatase,
Blood-to-tissue transport of [18F]2-fluoro-2-deoxyglucose (FDG) and [11C]O-methylglucose (CMG) was compared by dynamic positron emission tomography in four patients with recent ischemic infarcts and in three patients with intracerebral tumors. Local blood volume, tracer transport from tissue to
The rate of coronary flow reaching the oxygen-linited heart appears to be crucial in determining the myocardial tissue metabolic response. The tissue metabolic response to anoxia, well studied in hearts perfused with anoxic media, differs in many important ways from the response to ischemia. In
Protein, hexose, amino sugar and sialic acid levels were determined in the perchlorosoluble fraction of serum from patients with myocardial infarct. Patients have significantly elevated mean values for all components. The hexose/perchlorosoluble protein and amino sugar/perchlorosoluble protein
Metabolomic approaches in prospective cohorts may offer a unique snapshot into early metabolic perturbations that are associated with a higher risk of cardiovascular diseases (CVD) in healthy people. We investigated the association of 105 serum metabolites, including acylcarnitines, amino acids,
The effects of occlusion of the left anterior descending coronary artery on a variety of metabolic parameters was examined in both infarcted and noninfarcted areas of the dog heart. These included mitochondrial performance, glycolysis, in vitro contractility, and regional myocardial blood flow.
Myocardial infarction produces significant abnormal liver functioning. In the present study the hepatoprotective effect of tincture of Crataegus (TCR) in myocardially infarcted rats was investigated. The oral administration of TCR to rats for 30 days afforded good protection against
The purpose of this study was to compare the in vitro metabolic changes in mouse peritoneal macrophages exposed to sera of CHD patients and healthy donors. Oxidative (metabolic) burst was estimated by the activity of one of the limiting enzymes of hexose monophosphate shunt--glucoso-6-phosphate