hexose/inflammation

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Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom and a method for their preparation. These compounds exhibit

Methods of treating inflammation using cell adhesion inhibitors

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TECHNICAL FIELD The invention relates to compounds useful in the treatment of inflammation, allergic reactions, autoimmune diseases, and related conditions. More specifically, the invention concerns substituted lactose that binds to selectin receptors and to pharmaceutical compositions containing

Disubstituted and deoxy disubstituted derivatives of .alpha.-D-mannofuranosides and .beta.-L-gulofuranosides having anti-inflammatory and anti-proliferative activity

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the novel design and synthesis of disubstituted or deoxydisubstituted .alpha.-D-mannofuranosides and .beta.-L-gulofuranosides and intermediates for preparing these disubstituted derivatives. More specifically,

Substituted lactose and lactosamine derivatives as cell adhesion inhibitors

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TECHNICAL FIELD The invention relates to compounds useful in the treatment of inflammation, allergic reactions, autoimmune diseases, and related conditions. More specifically, the invention concerns substituted lactose and lactosamines that bind to the endothelial leukocyte adhesion molecule-1

Substituted lactose and lactosamine derivatives as cell adhesion inhibitors

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TECHNICAL FIELD The invention relates to compounds useful in the treatment of inflammation, allergic reactions, autoimmune diseases, and related conditions. More specifically, the invention concerns substituted lactose and lactosamines that bind to the endothelial leukocyte adhesion molecule-1

Glucose uptake inhibitors

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FIELD OF THE INVENTION This invention provides compounds that modulate glucose uptake activity. Compounds of the invention are useful for treating diseases, including cancer, autoimmune diseases and inflammation, infectious diseases, and metabolic diseases. BACKGROUND OF THE INVENTION Glucose

2-Substituted-1H-benz[de]-isoquinoline-1,3(2H)-diones

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BACKGROUND OF THE INVENTION Various 2-[(substituted heterocyclic)alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones having central nervous system and anti-inflammatory activity are disclosed by Wade et al. in U.S. Pat. Nos. 3,935,227; 3,940,397; 3,940,398; 3,947,452; and 3,959,286. Also, Schenker in U.S.

Derivatives of monosaccharides as cell adhesion inhibitors

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FIELD OF INVENTION This invention generally relates to the derivatives of 5,6-dideoxy-.alpha.,D-5-epiglucofuranose, 5,6-dideoxy-.alpha.,D-5-epiallofuranose, 5,6-dideoxy-.alpha.,D-5-epimannofuranoside, 5-deoxy-.alpha.,D-lyxofuranoside, 5-deoxy-.alpha.,D-xylofuranose, 5-deoxy-.alpha.,D-ribofuranose,

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