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Imidazole derivatives for treating myocardial infarction
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The present invention relates to imidazole derivatives and salts thereof, to their synthesis and intermediates therefor, to pharmaceutical formulations containing such compounds and to the use of these compounds in medicine.
Thromboxane A.sub.2 (TXA.sub.2), a potent stimulator of blood platelet
Non-peptidic GAPDH aggregation inhibitor
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TECHNICAL FILED
The present invention relates to a non-peptide aggregation inhibitor of GAPDH (glyceraldehyde-3-phosphate dehydrogenase).
BACKGROUND ART
Alzheimer's disease, which causes cognitive disorder as a major symptom, requires immediate attention to take countermeasures. The correction
Pharmaceutical composition for neurotrophic action
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This application is the National Stage of International Application No. PCT/JP99/02144, filed on Apr. 22, 1999.
TECHNICAL FIELD
The present invention relates to a pharmaceutical composition for neurotrophic action having an excellent properties.
BACKGROUND ART
Proteins such as nerve growth factor
Acylsulfonamide derivative
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FIELD OF THE INVENTION
This invention relates to acylsulfonamide derivatives, more particularly to a novel acylsulfonamide derivative which has the activity to inhibit acetyl-CoA carboxylase (also to be referred to as "ACC" hereinafter).
BACKGROUND ART
It has been revealed in recent years that
Inhibitor of vascular permeability enhancer
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method for preventing or treating a brain edema, an intracranial hemorrhage (especially a recurrence of an intracranial hemorrhage and so on) and a cerebral infarction, which comprises administering a
Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
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The present invention relates to novel substituted vinylcarboxylic acid derivatives which possess the action to inhibit specifically the thromboxane A.sub.2 (TXA.sub.2) synthetase.
TXA.sub.2 is a metabolite of arachidonic acid and has the platelet aggregating action. Therefore, it has been known
Carbacyclins, their preparation and pharmacological use
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BACKGROUND OF THE INVENTION
The present invention relates to new prostacyclin derivatives, a method for producing them and their use as medicines.
In German laid-open applications DE-OS 28 45 770, 29 00 352, 29 02 442, 29 04 655, 29 09 088 and 29 12 409, analogs of (5E)- and
Lipoxygenase inhibiting 1-arylalkyl-, 1-arylthio-, and 1-aryloxypyrazole-4,5-diones
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The invention relates to pyrazoledione derivatives, processes for their preparation, their use in the prophylaxis and therapy of diseases of the respiratory tract, inflammations, rheumatism, thromboembolic diseases, ischaemias and infarcts, cardiac arrhythmias and arteriosclerosis, and mixtures of
Benzoxazepine derivatives and their salts and medicaments containing the same
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TECHNICAL FIELD
The present invention relates to novel benzoxazepine derivatives and their salts. More particularly, it relates to novel benzoxazepine derivatives and their salts useful as medicaments for the treatment of anxiety neurosis, phobias, obsessive-compulsive disorders, schizophrenia,
Diamine derivatives
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TECHNICAL FIELD
The present invention relates to novel compounds which inhibit activated blood coagulation factor X (hereinafter abbreviated as "FXa") to exhibit a potent anticoagulant effect and can be orally administered, and anticoagulants or agents for preventing and/or treating thrombosis or
Diamine derivatives
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TECHNICAL FIELD
The present invention relates to novel compounds which inhibit activated blood coagulation factor X (hereinafter abbreviated as "FXa") to exhibit a potent anticoagulant effect and can be orally administered, and anticoagulants or agents for preventing and/or treating thrombosis or
Diamine derivatives
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TECHNICAL FIELD
The present invention relates to novel compounds which inhibit activated blood coagulation factor X (hereinafter abbreviated as "FXa") to exhibit a potent anticoagulant effect and can be orally administered, and anticoagulants or agents for preventing and/or treating thrombosis or
Fused heterocyclic compounds, having angiotensin II antagonistic activity
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FIELD OF THE INVENTION
The present invention relates to novel fused heterocyclic compounds having potent pharmacological actions and intermediates for the preparation thereof. More particularly, the present invention relates to fused heterocyclic compounds having potent anti-hypertensive activity
Thienoimidazole derivatives, their production and use
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FIELD OF THE INVENTION
This invention relates to novel thienoimidazole derivatives having potent pharmacological actions and intermediates for the synthesis thereof.
More particularly, the present invention relates to compounds represented by the general formula (I): ##STR2## wherein the ring A is a
Benzimidazole derivatives, their production and use
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FIELD OF THE INVENTION
The present invention relates to novel benzimidazole derivatives having potent pharmacological actions and intermediates for the preparation thereof. More particularly, the present invention relates to compounds having potent anti-hypertensive activity and strong angiotensin
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