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iva/stroke

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omega-agatoxin IVA and excitotoxicity in cortical neuronal cultures.

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Because the P- and Q-type Ca2+ channel antagonist omega-agatoxin IVA inhibits glutamate release, agatoxin-related drugs could have a role in the treatment of excitotoxic neurologic disorders such as stroke. We examined the effect of omega-agatoxin IVA on excitotoxicity (lactate dehydrogenase

Heart and Cardiovascular Involvement in Patients with Mucopolysaccharidosis Type IVA (Morquio-A Syndrome).

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BACKGROUND Mucopolysaccharidosis (MPS) IVA is a rare lysosomal storage disorder with multiple skeletal and non-skeletal abnormalities requiring multiple surgical interventions. It is well known that patients with MPS IVA suffer from tachycardia, but cardiac and hemodynamic alterations have not been

Capturing subject variability in fMRI data: A graph-theoretical analysis of GICA vs. IVA.

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BACKGROUND Recent studies using simulated functional magnetic resonance imaging (fMRI) data show that independent vector analysis (IVA) is a superior solution for capturing spatial subject variability when compared with the widely used group independent component analysis (GICA). Retaining such
Diabetes mellitus substantially increases the risk of stroke and enhances brain's vulnerability to ischemia insult. In a previous study, Chikusetsu saponin IVa (CHS) pretreatment was proved to protect the brain from cerebral ischemic in normal stroke models. Whether CHS could attenuate cerebral
Background: Vascular age (VA) has recently emerged for CVD risk assessment and can either be computed using conventional risk factors (CRF) or by using carotid intima-media thickness (cIMT) derived from carotid ultrasound (CUS). This

Treating acute ischemic stroke in a patient with multiple sclerosis: A challenging issue.

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Multiple sclerosis (MS) is a chronic disease characterized by inflammation, demyelination and neurodegeneration in the central nervous system. Recent studies suggested that patients with MS might have a greater risk of ischaemic stroke (IS). IS treatment with intravenous alteplase (IVA) in MS has
BACKGROUND Attention deficits are common post stroke and result in poorer functional outcomes. This study examined the frequency of attention deficits after incident stroke and their correlates. METHODS Attention of 94 stroke survivors was assessed using the Bells test, Trails Making Test A/B, 2.4-
High-resolution vessel wall imaging (HRVWI) by MRI is a novel noninvasive imaging tool which provides direct information regarding vessel wall pathologies. The utility of HRVWI in differentiating various intracranial vasculopathies among ischemic stroke is still

Pneumococcal pneumonia and the risk of stroke: a population-based follow-up study.

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BACKGROUND To investigate the risk of developing stroke in patients hospitalized following a diagnosis of pneumococcal pneumonia. METHODS The study cohorts comprised of patients hospitalized with a principal diagnosis of pneumococcal pneumonia (n = 745), with a random sampling of control individuals

Quantifying motor recovery after stroke using independent vector analysis and graph-theoretical analysis.

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The assessment of neuroplasticity after stroke through functional magnetic resonance imaging (fMRI) analysis is a developing field where the objective is to better understand the neural process of recovery and to better target rehabilitation interventions. The challenge in this population stems from

The effectiveness of cognitive rehabilitation in improving visual and auditory attention in ischemic stroke patients.

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The present study aimed to investigate the effectiveness of a cognitive rehabilitation program in improving the visual and auditory attention performance in stroke patients. The research method was quasi-experimental with a pre-intervention, post-intervention and follow-up design and control group.

Recurrent Stroke Due to Metastatic Pulmonary Tumor Emboli as an Important Clinical Entity.

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We present an autopsy case of repetitive stroke due to tumor emboli, indistinguishable from thromboembolism with a hypercoagulable state in its clinical course. A 72-year-old man diagnosed with stage IVA oropharyngeal squamous cell carcinoma received chemoradiotherapy. Follow-up imaging revealed
The NuPulseCV intravascular ventricular assist system (iVAS) provides extended duration ambulatory counterpulsation via a durable pump placed through the distal subclavian artery.We performed a prospective, single-arm, multicenter, US Food and Drug
OBJECTIVE Our objective was to present normative data from 70-year-olds on the Integrated Visual and Auditory Continuous Performance Test (IVA), a computerized measure of attention and response control. METHODS 640 participants (330 men and 310 women), all aged 70 years, completed the IVA, as well

Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts.

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Heart rate reduction (HRR) is an important target in the management of patients with chronic stable angina. Most available drugs for HRR, such as β-blockers, have adverse effects, including on cardiac energy substrate metabolism, a well-recognized determinant of cardiac homeostasis. This study aimed
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