4 resultat
Vasodepressor mechanism of lycorenine (an alkaloid of Lycoris radiata Herb.) was investigated in anesthetized rats. Lycorenine (1--10 mg/kg i.v.) produced dose-related decreases in blood pressure and heart rate and tachyphylaxis developed with repeated injections. In the blood-perfused rat
After ultrasonic-assisted extraction, four lycoris radiata alkaloids: galanthamine, homolycorine, lycorenine, and tazettine were determined by capillary electrophoresis electrochemiluminescence. Polyvinylpyrrolidone was added to the running buffer (RB) to obtain better resolution. Experimental
Blood pressure responses to lycorenine were investigated in rats and dogs. Lycorenine (10--40 mg/kg p.o.) produced a decrease in blood pressure in conscious rats which was greater in hypertensive rats than in normotensive rats. In conscious dogs, lycorenine (5 or 10 mg/kg i.v.) produced rises in
OBJECTIVE
To study the Amaryllidaceae alkaloids of the bulbs of Lycoris radiata.
METHODS
The chemical constituents were isolated and purified by various chromatographic techniques, and the chemical structures were elucidated on the basis of spectroscopic methods. In addition, the antiviral