medullary sponge kidney/citrate

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The impact of potassium citrate therapy in the natural course of Medullary Sponge Kidney with associated nephrolithiasis.

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The present study was carried out to evaluate the effectiveness of medical therapy with potassium citrate in preventing calculosis complicating Medullary Sponge Kidney (MSK) without renal acidification defects.In a open, uncontrolled, retrospective

Long-term treatment with potassium citrate and renal stones in medullary sponge kidney.

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OBJECTIVE Medullary sponge kidney (MSK) is a renal malformation typically associated with nephrocalcinosis and recurrent calcium stones. Incomplete distal renal tubular acidosis, hypocitraturia, and hypercalciuria are common. For stone prevention, patients with MSK generally receive the standard

Urinary acidification and urinary excretion of calcium and citrate in women with bilateral medullary sponge kidney.

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Urinary acidification ability, acid-base status and urinary excretion of calcium and citrate were evaluated in 10 women with bilateral medullary sponge kidney (MSK) and in 10 healthy women. Patients with MSK had higher fasting urine pH compared to normal controls (p < 0.01). Four patients had

Bone disease in medullary sponge kidney and effect of potassium citrate treatment.

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OBJECTIVE In medullary sponge kidney (MSK)-a common malformative renal condition in patients with calcium nephrolithiasis-hypercalciuria, incomplete distal renal tubular acidosis, and hypocitraturia are common. Clinical conditions with concomitant hypercalciuria and/or incomplete distal renal

Combined treatment of medullary sponge kidney by EDTA potassium citrate and extracorporeal shock wave lithotripsy.

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A case of successful renal calculus dissolution by the combined treatment which consists of irrigation with ethylenediaminetetraacetic acid (EDTA), potassium citrate, and extracorporeal shock-wave lithotripsy (ESWL) is described here. Renal irrigation via nephrostomy, which was the main treatment,

Re: The Impact of Potassium Citrate Therapy in the Natural Course of Medullary Sponge Kidney with Associated Nephrolithiasis.

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Contributory metabolic factors in the development of nephrolithiasis in patients with medullary sponge kidney.

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Whether specific metabolic abnormalities are related to nephrolithiasis in patients with medullary sponge kidney (MSK) remains a debated issue. The purpose of this study is to determine metabolic disorders in patients with MSK and nephrolithiasis compared with idiopathic calcium-stone-forming

[Clinical studies on medullary sponge kidney evaluated from urolithiasis].

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Thirty eight patients with medullary sponge kidney (MSK) were detected (4.3%) in 881 patients with urolithiasis diagnosed by drip infusion pyelography in 12 years from January 1974 to December 1985. Those with MSK were studied clinically and as to metabolism of urolithiasis. The results obtained

Nephrocalcinosis in adolescent girl with medullary sponge kidney and mild hemihypertrophy: A case report.

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Medullary sponge kidney (MSK) is a rare congenital abnormality characterized by cystic dilatation of the medullary collecting tubules. The disorder is likely to be complicated by nephrocalcinosis, urolithiasis, tubular dysfunctions, and urinary tract infections. In addition, it may be

Medullary Sponge Kidney: Current Perspectives.

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Medullary Sponge Kidney (MSK) disease is a rare congenital malformation of the distal nephron where cystic dilatation is appreciable in the collecting ducts and renal papillae. Most cases of the malformation are thought to arise from a malfunction within neurotrophic factor and tyrosine kinase

Development of metaphylaxis in calcium urolithiasis: a restriction of conventional drug therapy.

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Between 1978 and 1992 (mean 9.2 years), metaphylaxis was introduced to 110 patients originally hospitalized for recurrent urinary calcium stones (mostly bilateral or multiple). Patients with hyperparathyroidism or with sponge kidney were excluded from the study. Until 1984, the condition had been

[Pathogenesis of renal calculi].

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The prevalence of nephrolithiasis (12% of the population) is directly related to environmental risk factors including nutrition. Correlations have been demonstrated between activity of renal stone disease and excessive protein intake or low fiber diets, and cause-and-effect relationships have been

Genetic versus environmental factors in renal stone disease.

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The dietary habits of renal stone formers appear to differ from those of the general population. Renal stone formers seem to eat more oxalate, more flesh protein and less vegetable fibres than their normal counterparts. Often their urine volume is low. These are environmental factors which govern

[Renal acidification mechanism disorders in patients with osteoporosis].

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Eight patients (6 women and 2 men) with osteoporosis caused or aggravated by renal acidification defects are presented. Three of the female patients were premenopausal; the others were 9, 20 and 22 years postmenopausal, and two of them were on hormonal replacement therapy. Two patients had

Metabolic abnormalities in patients with caliceal diverticular calculi.

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OBJECTIVE We determined the incidence and spectrum of metabolic abnormalities in patients with caliceal diverticular calculi. METHODS Five men and 9 women with caliceal diverticular calculi underwent metabolic evaluation, including determination of serum electrolytes, calcium, phosphate and uric

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