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5 resultat
Inhibition of mitogen-activated protein kinase (MAPK) pathway: a selective therapeutic strategy against melanoma
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention in the field of biochemistry and medicine relates to methods to kill melanoma cells and treat melanoma tumors in a selective manner using compositions that inhibit the mitogen-activated protein kinase (MAPK) pathway.
2. Description
170kD membrane-bound protease useful in diagnosis of malignant cellular transformation
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is directed to a novel membrane protease isolated from malignant human melanoma cells such as the LOX line and RPMI7951 line. The invention is further directed to diagnosis of cellular transformation involving the use of
Treatment of osteocarcinoma with alpha-1--antitrypsin or secretory leucocyte protease inhibitor
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FIELD OF THE INVENTION
The present invention relates to the treatment of cancer and to the pain associated with cancer. The compositions utilized consist of protease inhibitors which prevent the proliferation of cancer cells and bind with the protease released by the cancer cells.
BACKGROUND OF THE
Cosmetic compositions and methods
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FIELD
The present disclosure is directed to cosmetic compositions and methods for up-regulating proteasomal protease activity.
BACKGROUND
Skin tone evenness and/or the appearance of hyperpigmentary spots, such as solar lentigines (age spots), are common concerns among beauty conscious consumers. As
Anti-metalloprotease antibody for diagnosis and treatment of cancers
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INCORPORATION-BY-REFERENCE OF MATERIAL ELECTRONICALLY SUBMITTED
Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing su currently herewith and identified as follows: One 8,709 Byte SCII (Text) filed named "726179_ST25.TXT," created Feb. 26,
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