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melasma/atrofi

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[Degeneration of Dubreuilh's melanosis of the foot].

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[Degenerating Dubreuilh's melanosis. Simple excision. Recovery for 2-1/2 years].

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The clinicoaetiological, hormonal and histopathological characteristics of melasma in men.

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BACKGROUND Melasma is relatively uncommon in males, and there is a paucity of data on male melasma, including its clinical pattern, triggering factors, endocrine profile and histopathological findings. OBJECTIVE To characterize the clinical findings and aetiological factors, including hormonal and
BACKGROUND Aggravated melasma after treatment is vulnerable to stimulation, can easily deteriorate, and may be distressing without proper management. OBJECTIVE To retrospectively assess the effectiveness and safety of combination therapy using low-fluence Q-switched neodymium-doped yttrium aluminum

Riehl Melanosis

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Facial melanoses affecting the face and neck region are of considerable concern to darker-skinned people. Although many facial melanoses, such as melasma, are well defined clinically, rendering them easy to diagnose, others have overlapping clinical morphology as well as histopathology. Riehl

[Isolated ocular melanosis. Apropos of a case].

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A case of an eighteen month child with ocular melanocytosis is reported. The authors describe clinicopathological features of the affection. Ocular melanocytosis is a neural crest disorder more frequently found in pigmented populations. Differential diagnosis are naevus of Ota, blue sclera disease

Industrial melanism in the peppered moth is not associated with genetic variation in canonical melanisation gene candidates.

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Industrial melanism in the peppered moth (Biston betularia) is an iconic case study of ecological genetics but the molecular identity of the gene determining the difference between the typical and melanic (carbonaria) morphs is entirely unknown. We applied the candidate gene approach to look for

Pathogenesis of generalized melanosis with melanuria and melanoptysis secondary to malignant melanoma.

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A case of disseminated malignant melanoma with generalized melanosis of the skin and other tissues, melanuria, melanoptysis, and a dark brown blood serum is reported. The reticuloendothelial system contained large amounts of melanin pigment. Lysis of degenerating pigment-loaded melanoma cells in
A survey of seven cases of Becker's melanosis has been performed. Their clinical characteristics are described. The photonic microscopy showed the basal layer overloaded with melanin, some alterations of the superficial dermis, and the appearance of cytoid bodies. The electron microscopy pointed out

Analysis of the effect of different doses of oral tranexamic acid on melasma: a multicentre prospective study.

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Melasma is pale brown to dark brown hyperpigmentation of the facial skin that commonly affects women of reproductive age. Treatment methods for melasma include oral and topical use of vitamin C, hydroquinone ointment, and laser treatment, with unsatisfactory results. Tranexamic acid

Rationale for the use of topical corticosteroids in melasma.

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Corticosteroids have been combined with other agents in the treatment of melasma for years. In early studies by Kligman and Willis, topical dexamethasone as monotherapy produced little depigmentation even after 3 months of therapy. A significant concern is that topical corticosteroids used alone in

An unusual case of neurocutaneous melanosis.

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The neurocutaneous melanosis (NCM) is a rare, neuroectodermal dysplasia defined by the association of giant or multiple, nonmalignant pigmented cutaneous nevi with leptomeningeal melanosis or melanoma. As a rule, the cerebral pathological substratum is characterized by a melanocytic infiltration of

A semiquantitative light and electron microscopic analysis of histopathologic changes in photochemotherapy-induced freckles.

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Photochemotherapy(PUVA)-induced freckles were found in 25 patients (41%) who had received more than 1,000 J/cm2 of PUVA. The patients had been treated with PUVA for more than 2 years, with more than 150 exposures before PUVA lentigines appeared on the thighs, the upper arm, the mid-lower arm, the

Is malignant melanoma arising in a Hutchinson's melanotic freckle a separate disease entity?

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Several features which distinguish malignant melanoma arising in a Hutchinson's melanotic freckle (HMFM) from other types of malignant melanoma (MM) are described. Forty-eight patients with HMFM of the head and neck region were compared with 98 patients with MM of the head and neck region. All
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