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Transdermal nicotine compared with oral prednisolone therapy for active ulcerative colitis.

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BACKGROUND Ulcerative colitis is largely a disease of non-smokers. Previous controlled trials have shown benefit with transdermal nicotine when given with 5-aminosalicylic acid in active disease but not when given alone as maintenance therapy. OBJECTIVE To examine nicotine alone compared with

Cases from the Osler Medical Service at Johns Hopkins University. Diagnosis: P. carinii pneumonia and primary pulmonary sporotrichosis.

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PRESENTING FEATURES: A 53-year-old man who had human immunodeficiency virus (HIV) presented to the Johns Hopkins Hospital with a 3-month history of increasing dysphagia, cough, dyspnea, chest pain, and an episode of syncope. His past medical history was notable for oral and presumptive esophageal

Characterizing health behaviors and infectious disease prevalence among Filipino street children.

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OBJECTIVE To describe health problems and social, environmental, and health behavior characteristics among street children in Manila, Philippines. METHODS A cross-sectional survey and clinical tests that included chest radiographs blood, urine, and stool samples were completed with 179 street

[Eradication of Helicobacter pylori in peptic ulcer and chronic gastritis. A randomized clinical trial].

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BACKGROUND The Helicobacter pylori (Hp) is found in patients with gastritis and peptic ulcer approximately in up to 80 percent. The eradication rates of 80 to 90 percent are achievable with some regimens. OBJECTIVE Evaluate two regimens for H pylori eradication in gastritis and peptic

Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.

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A 48-year-old man residing in a mental health department inpatient program with a history of schizoaffective disorder presented to the emergency department with a chief complaint of fever and intense abdominal pain for one day. The patient stated he initially fell in the shower and afterwards

[Peptic ulcer with hemorrhage. An analysis of hospital discharges].

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BACKGROUND The gastric and duodenal ulcer is the most common cause of gastrointestinal bleeding in 25% of patients, and accounting annually for approximately 50-100 admissions per 100,000 population. OBJECTIVE To determine prevalence of gastrointestinal bleeding in hospital admission, according to

Drugs and gastric damage.

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The effects of aspirin, salicylate formulations and substitutes, smoking (nicotine), indomethacin, corticosteroids, phenylbutazone, ethanol, caffeine and reserpine on the gastric mucosa are discussed. The damaging effects of the drugs are considered in terms of the gastric mucosal barrier, gastric

Fecal occult blood test for colorectal cancer screening: an evidence-based analysis.

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The colorectal cancer (CRC) screening project was undertaken by the Medical Advisory Secretariat (MAS) in collaboration with the Cancer Care Ontario (CCO).In November 2007, the Ontario Health Technology Advisory Committee (OHTAC) MAS to conduct an evidence-based analysis of the available data with

Body iron stores and risk of colonic neoplasia.

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BACKGROUND Body iron stores and dietary iron intake have both been shown to be positively associated with subsequent risk of colon cancer. This finding comes from a cohort study involving 14,000 men, but the positive association occurred in only 12 cases. OBJECTIVE We performed a case-control study

Acute Upper Gastrointestinal Bleeding in a Tertiary Care Centre of Nepal.

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BACKGROUND AUGIB is characterized by hematemesis or melena or both. Peptic ulcers and variceal bleed account for majority of cases. Use of proton pump inhibitors in current era is associated with a gradual reduction in burden of peptic ulcer disease. We conducted this study to look into the cause of

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