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Posterior microphthalmos and papillomacular fold-associated cystic changes misdiagnosed as cystoid macular edema following cataract extraction.

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OBJECTIVE Novel spectral-domain optical coherence tomography (SD-OCT) findings in posterior microphthalmos (PM) include cystoid changes in the papillomacular fold (PMF). These changes may be misdiagnosed as cystoid macular edema (CME) and may trigger unnecessary treatment including intravitreal

Efficacy of topical dorzolamide therapy for cystoid macular edema in a patient with MFRP-related nanophthalmos-retinitis pigmentosa-foveoschisis-optic disk drusen syndrome.

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OBJECTIVE Mutations in the MFRP (membrane-type frizzled-related protein) gene leads to an entity characterized by retinitis pigmentosa, nanophthalmos, optic disk drusen, and macular changes, originally described as foveoschisis. Despite the association of MFRP gene mutation and increase in macular

Bilateral microphthalmos with colobomatous orbital cyst and de-novo balanced translocation t(3;5).

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A term Caucasian male infant, born to a healthy non-related couple, was noted at birth to have bilateral edema and bluish discoloration of the lower eyelids. On physical examination, the eye globes were not visualized and hypertelorism was noted. Radiological imaging revealed large bilateral orbital

Nanophthalmos and hemiretinal vein occlusion: A case report.

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Many risk factors have been linked to retinal vein occlusions (RVOs) whether central or branch retinal vein occlusion. Ocular risk factors include glaucoma and hypermetropia. Controversy exists to whether short axial length is a risk factor for retinal vein occlusions. We report an extreme case that

Scanning electron microscope evaluation of the corneal endothelium in a case of unilateral microphthalmos with retrobulbar cyst in the pigmented rabbit.

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A case of unilateral microphthalmos with a sizeable retrobulbar cyst, totally dysplastic retina, and gross nerve head coloboma is reported in an otherwise normal pigmented rabbit. Despite the gross abnormality of the posterior part of the globe, an iris sectoral coloboma, and abnormal lentoid body,

A novel crumbs homolog 1 mutation in a family with retinitis pigmentosa, nanophthalmos, and optic disc drusen.

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OBJECTIVE The purpose of this study is to identify the genetic defect in a Turkish family with autosomal recessive retinitis pigmentosa, nanophthalmos, and optic disc drusen. METHODS Ophthalmological examinations consisted of measuring the best-corrected visual acuity and the refractive error,

Pseudophakic/aphakic corneal edema--morphometric predisposing factors analysis based on the fellow eye examination.

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OBJECTIVE To find morphometric factors predisposing to the development of corneal decompensation following cataract surgery. METHODS Study group consisted of 50 patients after keratoplasty performed as pseudophakic/aphakic corneal edema (PCE/ACE) treatment. Control group formed 50 patients after

Nanophthalmos and acquired retinoschisis.

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OBJECTIVE To report three cases of nanophthalmos associated with acquired (senile) retinoschisis. METHODS Observational case series. METHODS Complete ophthalmologic evaluation (including funduscopy with scleral indentation, total axial length measurement with A-scan, optical coherence tomography

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy.

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Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of podocytes are on the market and model systems for

Optical coherence tomography of bilateral posterior microphthalmos with papillomacular fold and novel features of retinoschisis and dialysis.

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OBJECTIVE To report a case of retinoschisis and dialysis associated with bilateral posterior microphthalmos and papillomacular fold. METHODS Observational case series. METHODS Complete ophthalmologic examination of three of five siblings presenting with bilateral posterior microphthalmos and

Relative anterior microphthalmos: morphometric analysis and its implications for cataract surgery.

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OBJECTIVE To evaluate morphometric data and risk factors for complications of cataract surgery in patients with relative anterior microphthalmos (RAM). METHODS Retrospective, comparative study (Part I) and matched pairs analysis with controls (Part II). METHODS Sixty-two patients with RAM who

Cataract surgery in relative anterior microphthalmos.

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OBJECTIVE To determine the prevalence of relative anterior microphthalmos (RAM) and evaluate intraoperative performance and surgical outcome in eyes with RAM undergoing cataract surgery. METHODS Nested case-control series. METHODS One thousand four hundred consecutive patients undergoing cataract

Outcomes and Prognostic Factors of Cataract Surgery in Adult Extreme Microphthalmos with Axial Length <18 mm or Corneal Diameter <8 mm.

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OBJECTIVE To study the long-term visual outcomes, complications, and prognostic factors for cataract surgery in extreme microphthalmos. METHODS Prospective cohort study. METHODS Thirty eyes with simple microphthalmos (11 eyes, axial length [AL] <18 mm), complex microphthalmos (8 eyes, AL <18 mm),

Compound heterozygosity for a novel and a recurrent MFRP gene mutation in a family with the nanophthalmos-retinitis pigmentosa complex.

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OBJECTIVE To report a new familial case of the recently described autosomal recessive syndrome of nanophthalmos-retinitis pigmentosa-foveoschisis-optic disc drusen, which arises from compound heterozygosity for Membrane Frizzled-Related Protein (MFRP) mutations in a sibling pair of Mexican

Primary piggyback implantation of 3 intraocular lenses in nanophthalmos.

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We present a patient with bilateral nanophthalmos who had uneventful cataract extraction in the right eye with primary implantation of 3 intraocular lenses (IOLs) of 2 different materials: a 30 diopter (D) acrylic IOL and a 9 D silicone IOL in the capsular bag and a 30 D silicone IOL in the ciliary

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