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mitral valve insufficiency/kalium

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Atrial fibrillation (AF) is the most common cardiac arrhythmia. Valvular heart disease is a strong predictor, yet the underlying molecular mechanisms are unknown. The purpose of this study was to investigate the prevalence of somatic variants in AF candidate genes in an AF patient population
OBJECTIVE To study long-term effects of enalapril, an angiotensin-converting enzyme inhibitor, and hydralazine, an arteriodilator, on renin-angiotensin-aldosterone system and fluid balance before and after administration of furosemide. METHODS 22 dogs with clinical signs of congestive heart failure

[Treatment of mitral valve insufficiency in dogs with the ACE inhibitor enalapril. A clinical progress study].

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The efficacy and safety of the angiotensin converting enzyme inhibitor enalapril in dogs with naturally acquired class III or class IV heart failure was evaluated in this study. Eighteen small-breed dogs with insufficiency of their mitral valves, but without other diseases were included in this

Assessment of prognostic factors in patients undergoing surgery for non-rheumatic mitral regurgitation.

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Twenty-four patients who had undegone mitral valve surgery for pure non-rheumatic mitral regurgitation were studied non-invasively six months to six years postoperatively. The long-term results of operation were assessed on the basis of clinical history, echocardiography, and treadmill stress

Pharmacokinetics of nicorandil in dogs with mild mitral regurgitation.

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The aim of this study was to examine the pharmacokinetics of nicorandil, a hybrid of an adenosine triphosphate-sensitive potassium channel opener and a nitrate, and to estimate its clinical doses in dogs with mild mitral valve regurgitation (MR). Nicorandil (0.1, 0.3, and 1.0 mg/kg) was administered

Correlation of degree of left ventricular volume overload with clinical course in aortic and mitral regurgitation.

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The results of left ventricular volume studies using biplane angiocardiography are described in 20 patients with mitral regurgitation and in 27 patients with aortic regurgitation. In both lesions, a regurgitant fraction of over 60 per cent was likely to be associated with severe symptoms and most
OBJECTIVE To determine the efficacy and dose requirements of captopril to reduce functional mitral regurgitation in patients with dilated heart failure. METHODS A randomised double blind placebo controlled parallel arm trial. Incremental daily doses of 25 mg, 50 mg and 100 mg captopril used for a

Severe Mitral Regurgitation As a Result of Rupture of Mitral Valve Chordae Tendineae in a Patient With Graves Disease.

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Mitral valve prolapse is a common disorder, but severe mitral regurgitation (MR) as a result of rupture of mitral valve chordae tendineae is a rare manifestation of thyrotoxic heart disease. There are limited reports with respect to the onset of severe MR as a complication of Graves disease. We

Assessment of left ventricular functional preservation during isolated cardiac valve operations.

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To evaluate intraoperative changes in myocardial performance during valvular operations, ventricular functional measurements were obtained in 16 patients before and after elective cardiac valvular replacement. Six patients had mitral regurgitation, four had mitral stenosis, and six had calcific

[Autoantibodies: new upstream targets of paroxysmal atrial fibrillation in patients with congestive heart failure].

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OBJECTIVE The clinical implications of autoantibodies (Abs) were investigated as upstream indicators of paroxysmal atrial fibrillation in patients with congestive heart failure. METHODS Circulating Abs against myosin (M-Abs) detected by immunofluorescence, Abs against beta 1-adrenergic receptors

[Mitral valve replacement and closure of ventricular septal defect in the first two months of life].

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A 2-month-old female infant weighing 4.2 kg was admitted with severe congestive heart failure and respiratory distress. The patient was operated upon under a diagnosis of severe congenital mitral regurgitation and ventricular septal defect. There was thickening of the anterior leaflet and short

[Long-term follow-up study of bone mineral density in a patient with adult idiopathic Fanconi syndrome].

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A 64-year-old woman complaining of severe lumbar pain was admitted to our hospital because of the finding of pre-existing mitral valve regurgitation on examination. Laboratory data revealed the proximal type of renal tubular acidosis, renal glucosuria, phosphaturia, generalized aminoaciduria and

Alarming atrioventricular block and mitral valve prolapse in the Kearns-Sayre syndrome.

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Kearns-Sayre syndrome (KSS) is a multisystem mitochondrial disorder characterized by the invariant triad: onset before 20, progressive external ophthalmoplegia and pigmentary retinal degeneration, plus at least one of the following: complete (or not) heart block, cereberal dysfunction and CSF

Mitral and tricuspid valve repair and growth in unbalanced atrial ventricular canal defects.

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OBJECTIVE Congenital mitral and tricuspid valve abnormalities in unbalanced atrioventricular canal defects are complex. We designed procedures to both repair and induce growth of hypoplastic atrioventricular valves and ventricles to achieve 2-ventricle repairs. Midterm data were assessed for
Baseline plasma norepinephrine (NE) and epinephrine (EPI) concentrations were measured in dogs with naturally acquired heart failure (HF) caused by either degenerative mitral valve disease and mitral regurgitation (MR) or idiopathic dilated cardiomyopathy (DCM). Compared with controls (clinically
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