multiple chemical sensitivity/seizures

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MMPI-2 profiles of persons with multiple chemical sensitivity.

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We compared the MMPI-2 profiles of adults with multiple chemical sensitivity (MCS), epileptic seizures (ES), and nonepileptic seizures (NES). Both NES and MCS are medically unexplained conditions. In previous studies profiles associated with NES were elevated on scales Hs and Hy, compared with

Potential role of stress and sensitization in the development and expression of multiple chemical sensitivity.

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Chemical sensitivity in humans may be an acquired disorder in which individuals become increasingly sensitive to chemicals in the environment. It is hypothesized that in individuals with multiple chemical sensitivity (MCS), a sensitization process has occurred that is akin to behavioral

Does the kindling model of epilepsy contribute to our understanding of multiple chemical sensitivity?

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Multiple chemical sensitivity (MCS) is a phenomenon whereby individuals report an increased sensitivity to low levels of chemicals in the environment. Kindling is a model of synaptic plasticity whereby repeated low-level electrical stimulation to a number of brain sites leads to permanent increases

Levetiracetam improves symptoms of multiple chemical sensitivity: Case report.

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Multiple chemical sensitivity (MCS) is a disorder of unknown etiology with no effective treatment. Many clinicians accept that a diagnosis of somatic symptoms disorder (SSD) is an appropriate diagnostic category for MCS. We found that administration of levetiracetam improved recurrent symptoms of

Individual differences in neural sensitization and the role of context in illness from low-level environmental chemical exposures.

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This paper summarizes the clinical phenomenology of multiple chemical sensitivity (MCS), outlines the concepts and evidence for the olfactory-limbic, neural sensitization model for MCS, and discusses experimental design implications of the model for exposure-related research. Neural sensitization is

White paper: Neuropsychiatric aspects of sensitivity to low-level chemicals: a neural sensitization model.

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The present paper summarizes the proposed time-dependent sensitization (TDS) and partial limbic kindling model for illness from low-level chemicals; reviews and critiques prior studies on CNS aspects of multiple chemical sensitivity (MCS); and outlines possible experimental approaches to future

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