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multiple sclerosis/fetma
Länken sparas på Urklipp
Sida 1 från 48 resultat
Substituted 2,3-dihydro-1H-inden-1-one Retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
3H-imidazo[4,5-b]pyridin-5-ol derivatives useful in the treatment of GPR81 receptor disorders
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FIELD OF THE INVENTION
The present invention relates to certain 3H-imidazo[4,5-b]pyridin-5-ol derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the GPR81 receptor. Also provided by the present
Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient
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TECHNICAL FIELD
The present invention relates to a nitrogen-containing bicyclic compound or a pharmacologically acceptable salt thereof and a pharmaceutical composition comprising it as active ingredient.
More specifically, the present invention relates to (1) a compound of formula (I)
##STR00002##
Systems, methods and apparatus for differential air pressure devices
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The present application is also related to U.S. patent application Ser. No. 12/761,312, filed on Apr. 15, 2010, now abandoned, which is incorporated by referent herein in its entirety.
FIELD
The present invention relates to differential air pressure devices. More particularly, the present invention
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein
R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl,
R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Dual action recumbent exercise cycle
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BACKGROUND OF THE INVENTION
1. Field of Invention
The present invention generally relates to cycle exercisers and recumbent exercisers for physical therapy and/or general exercise as disclosed in U.S. Pat. No. 4,188,030, and more particularly, to the recumbent exercise machines described in U.S.
Methods of treating diseases associated with high-fat diet and vitamin A deficiency using retinoic acid receptor agonists
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FIELD
The invention relates to the treatment and prevention of various diseases or conditions caused by fat accumulation or vitamin deficiency.
BACKGROUND
After smoking, high fat diet is said to be the second most lethal habit, causing 300,000 deaths each year in the U.S. alone. High fat diet leads
Method of using abscisic acid to treat diseases and disorders
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the field of medical treatments for diseases and disorders. More specifically, the present invention relates to biologically active compounds that treat and prevent insulin resistance, impaired glucose tolerance,
Dipeptide phenyl ethers
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RELATED APPLICATION DATA
This invention is related to U.S. patent application Ser. No. 10/356,113, Filed Jan. 31, 2003, naming Bishwajit Nag, Abhijeet Nag, Shiv Kumar Agarwal, and Debendranath Dey as inventors, and entitled "Amino Acid Phenoxy Ethers". That application is incorporated herein by
Dipeptide phenyl ethers
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FIELD OF THE INVENTION
The present invention relates to novel dipeptide phenyl ethers of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and
Dipeptidyl peptidase IV inhibitors
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FIELD
Described are compounds of the formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof.
##STR00002##
Described herein is also a
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