multiple sclerosis/triglyceride

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Anti-annexin antibodies, cholesterol levels and disability in multiple sclerosis.

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So far, no studies have been conducted to evaluate possible correlations between lipid/lipoprotein levels and the anti-phospholipid antibody (aPL) positivity in multiple sclerosis (MS). In this cross-sectional study, we aimed to investigate the relationships between serum lipid profile and aPL

[Lipid profile evolution during the first year of treatment with beta interferon in multiple sclerosis].

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OBJECTIVE Treatment with beta interferon (IFNbeta) might alter the lipid profile. Plasmatic levels of total cholesterol and low density lipoprotein-cholesterol have been associated with the number of plaques in magnetic resonance of patients with demyelinating syndromes. METHODS Retrospective

New markers of early cardiovascular risk in multiple sclerosis patients: oxidized-LDL correlates with clinical staging.

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OBJECTIVE This study aimed to characterize a population of multiple sclerosis (MS) patients in terms of traditional and new cardiovascular risk factors and assess their putative correlation with clinical disease activity (evaluated by the Expanded Disability Status Scale [EDSS]). METHODS Thirty

Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis.

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Experimental autoimmune encephalomyelitis (EAE) is a T-cell-mediated, autoimmune disorder characterized by central nervous system inflammation and demyelination, features reminiscent of the human disease, multiple sclerosis (MS). Prior work in the EAE model has suggested that encephalitogenic T

Low high-density lipoprotein cholesterol and high triglycerides lipid profile in neuromyelitis optica spectrum disorder: Associations with disease activity and disability.

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Altered lipid metabolism is a feature of systemic autoimmune diseases. Dyslipidemia is associated with the disease activity and progression in patients with multiple sclerosis. However, in neuromyelitis optica spectrum disorder (NMOSD), changes in the lipid profile and the associations

Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study.

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To investigate associations between lipid profiles and fatigue in a cohort of progressive multiple sclerosis (MS) patients on a diet-based multimodal intervention.This pilot study included 18 progressive MS patients who participated in a prospective

Coronary heart disease risk between active and inactive women with multiple sclerosis.

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OBJECTIVE Physical activity is strongly recommended as a principal component of coronary heart disease (CHD) risk factor management aimed at favorably lowering abdominal fat accumulation, lowering levels of triglyceride (TG), raising levels of high-density lipoprotein-cholesterol (HDL-C), and

The Effectiveness of New Adiposity Indices on Plasma Lipid Profile in Patients With Multiple Sclerosis: A Cross-Sectional Study With A Body Shape Index, Body Roundness Index, and Visceral Adiposity Index

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Objective: This study aimed to determine the effectiveness of three different indices used to identify the effect of visceral adiposity on lipid profile markers in patients with multiple sclerosis. Methods: The study consisted of

The relationship between melatonin secretion and serum cholesterol in patients with multiple sclerosis.

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We have reported recently that nocturnal melatonin levels are reduced in a subgroup of patients with multiple sclerosis (MS). We have also noted in these patients a high incidence of hypercholesterolemia and propose that this may be linked to dysfunction of the pineal gland since pinealectomy in

Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.

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Epidemiological findings suggest a relationship between multiple sclerosis (MS) and cardiovascular disease (CVD) risk factors, although the nature of this relationship is not well understood. We used genome-wide association study (GWAS) data to identify shared genetic factors (pleiotropy) between MS

Comparison of serum apolipoprotein A-I between Chinese multiple sclerosis and other related autoimmune disease.

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BACKGROUND Serum apolipoprotein (apo) A-I was considered to be an immune regulator and could suppress pro-inflammatory cytokines generated by activated T cell in some autoimmune diseases. However, the change of serum apoA-I levels in multiple sclerosis (MS) patients is unknown. METHODS In the

[The metabolic characteristics of patients with multiple sclerosis].

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A comprehensive clinical and biochemical evaluation has been carried out in patients with multiple sclerosis (MS). Measured in the patients' blood were levels of cholesterol, triglycerides, malonic dialdehyde, and superoxidedysmutase activity. The interrelationship revealed between the above

Low fasting serum triglyceride level as a precocious marker of autoimmune disorders.

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The authors recently reported the occurrence of low fasting serum triglyceride (TG) and high free fatty acid (FFA) levels in idiopathic pulmonary fibrosis. TG estimation in diverse groups of patients with autoimmune disease or hyperactive immune response confirmed the occurrence of a similar

[Modifications of the lipid metabolism induced by interferon beta in multiple sclerosis patients and its relationship with the disease activity].

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BACKGROUND It has been recently suggested that total cholesterol and low density lipoproteins (LDL) levels can behave as biological markers of activity in demyelinating diseases. Thus, our aim has been to describe the modifications of the plasma levels of total cholesterol and triglyceride due to

A rapid ELISA-based serum assay for myelin basic protein in multiple sclerosis.

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We have developed a sensitive, ELISA-based assay to detect autoantibodies to myelin basic protein (MBP) in human serum. Autoantibody levels were measured in 98 normal healthy adults (age range 20-66) and 94 clinically definite multiple sclerosis (MS) cases (age range 18-63). Of the MS patients, 77%

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