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multiple sclerosis/tyrosine
Länken sparas på Urklipp
Sida 1 från 21 resultat
Treatment of multiple sclerosis (MS) and other demyelinating conditions using lofepramine in combination with L-phenylalanine, tyrosine or tyrptophan and possibly a vitamin B12 compound
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This invention relates to the treatment of Multiple Sclerosis (MS) and other Demyelinating Conditions.
Multiple sclerosis is a common and well known neurological disorder. It is characterised by episodic patches of inflammation and demyelination which can occur anywhere in the central nervous system
Treatment of multiple sclerosis (MS) and other demyelinating conditions using lofepramine in combination with L-phenylalanine, tyrosine or tryptophan and possibly a vitamin B12 compound
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This invention relates to the treatment of Multiple Sclerosis (MS) and other Demyelinating Conditions.
Multiple sclerosis is a common and well known neurological disorder. It is characterised by episodic patches of inflammation and demyelination which can occur anywhere in the central nervous system
Homopiperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use thereof
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FIELD OF THE INVENTION
This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a
Sulfamide piperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use therof
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FIELD OF THE INVENTION
This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a
Treatment of multiple sclerosis with masitinib
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The present invention relates to the treatment of multiple sclerosis (MS). The present invention relates to the administration of masitinib in an appropriate dosage regimen, and in particular in the treatment of MS.
BACKGROUND OF THE INVENTION
Multiple Sclerosis
Multiple Sclerosis (MS) is a common
Heterocyclic compounds as JAK receptor and protein tyrosine kinase inhibitors
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FIELD OF THE INVENTION
This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a
Substituted ethynyl heterobicyclic compounds as tyrosine kinase inhibitors
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TECHNICAL FIELD
The present invention describes a series of new compounds that display potent inhibition against Bruton's tyrosine kinase and, therefore, may provide a potential therapeutic approach to treating human cancers including B-cell lymphoma, and autoimmune diseases such as rheumatoid
Process for the preparation of copolymer-1 using a polymer supported dialkylamine initiator
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This application is a 371 of PCT/IN2009/000320, filed Jun. 4, 2009.
FIELD OF THE INVENTION
The present invention relates to a process for the synthesis of Copolymer-1 (Cop I). composed of L-alanine, L-lysine, L-glutamic acid and L-tyrosine for the treatment of multiple sclerosis.
BACKGROUND AND
Treatment of eosinophil or mast cell related disorders
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This application incorporates by reference a Sequence Listing submitted with this application as text file entitled "Sequence_Listing_12638-123-228.TXT" created on May 21, 2015 and having a size of 21,490 bytes.
1. FIELD
Provided herein are methods and uses involving antibodies that specifically
Inhibitors of C-FMS kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Methods of treating disease with random copolymers
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BACKGROUND OF THE INVENTION
An autoimmune disease results from an inappropriate immune response directed against a self antigen (an autoantigen), which is a deviation from the normal state of self-tolerance. Self-tolerance arises when the production of T cells and B cells capable of reacting against
Methods of treating disease with random copolymers
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BACKGROUND OF THE INVENTION
An autoimmune disease results from an inappropriate immune response directed against a self antigen (an autoantigen), which is a deviation from the normal state of self-tolerance. Self-tolerance arises when the production of T cells and B cells capable of reacting against
Copolymers for suppression of autoimmune diseases, and methods of use
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TECHNICAL FIELD
The invention relates to design of copolymers having particular amino acids in specific molar ratios, synthesized into polypeptides of predetermined length and capable of suppression of symptoms and frequency of recurrent episodes of an autoimmune disease.
BACKGROUND
Multiple
Random pentapolymer for treatment of autoimmune diseases
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FIELD OF THE INVENTION
The present invention relates generally to a synthetic linear random pentapolymer comprising alanine, glutamic acid, lysine, tyrosine and phenylalanine and use thereof for treating autoimmune diseases, in particular multiple sclerosis.
BACKGROUND OF THE INVENTION
A high
Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
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TECHNICAL FIELD
The present disclosure relates to a class of substituted hetero-bicyclic compounds of formula (I), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, hydrates, N-oxides, co-crystals, pharmaceutically acceptable salts and pharmaceutical compositions containing them. The
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