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Roflumilast in Non-CF Bronchiectasis Study (2019)

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In a 4-week crossover study in 38 patients with COPD, roflumilast 500μg daily significantly reduced sputum absolute neutrophil count, IL-8 and neutrophil elastase compared with placebo treatment. Interestingly, the mechanism of anti-neutrophilic inflammation with roflumilast treatment in patients

Banana Cultivars and Exercise Performance and Recovery

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The research procedures will be conducted at the Human Performance Laboratory (Room 1201, Plants for Human Health Institute Building, 600 Laureate Way), operated by Appalachian State University at the North Carolina Research Campus (NCRC) in Kannapolis, NC. Participants will come here for

Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder

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The study subjects are bipolar depressive patients seeking outpatient treatment for bipolar affective disorder in the psychiatric outpatient clinic in Heath Unit System of the Network of Outpatient Hospital of the State University of Londrina , and tobacco use disorder according of criteria

Impact of Exposure to Environmental Pollutants on Birth Outcomes in an Israeli Cohort

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Objectives and hypothesis The scale and diversity of chemicals in worldwide use today is vast, ranging from pharmaceuticals and food products, to plastics, gasoline, and semiconductor chips. Many of these chemicals are released into the environment where they are found in air, water, soil, in house

The Neural Basis of Cue-Elicited Cigarette Craving and Its Control

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Objective: Drug craving is a motivational state associated with a conscious desire to consume a drug (Fredrickson et al., 1995; Drummond, 2001). When drug abusers see drug-related cues, cue-elicited drug craving is induced (Drummond, 2001). The main goal of this investigation is to ascertain the

Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation

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Background: Cannabis sativa contains over sixty cannabinoids, including delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). CBD lacks psychoactivity and may attenuate the subjective effects produced by THC. The ratio of THC:CBD in illicit cannabis in the US is approximately 20:1.

Efficacy Study of Galantamine for Cognitive Impairments in Schizophrenia

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Patients with schizophrenia are characterized by a broad range of neurocognitive abnormalities. These include impairments in attention; eye-tracking; visual and verbal memory; working memory; processing speed; and sensory gating, as measured by P50. These impairments are major determinants of poor

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